Applications in Oncology: An Overview



Treatment of patients with cancer requires appropriate histological diagnosis and, more importantly, staging of the disease using the least invasive and most sensitive and specific procedures. Over the last decades, several studies have demonstrated immense contribution of nuclear medicine to the management of cancer. Positron emission tomography (PET) scanning has added significant clinical value in evaluating cancer patients. PET is an imaging modality that is used to provide a three-dimensional image of functional changes in the body. PET is commonly used to detect and stage different types of cancer. Accurate information about diagnosis and staging of disease is critical for planning the most appropriate treatment strategy. PET has also been used to monitor therapy. The rationale for this is that the early detection of disease that is not responding to treatment could allow for a change to a more effective treatment strategy. PET scanning has, therefore, been used as a tool in diagnosis, staging, restaging, and possibly follow-up of cancer patients. Another potential contribution of PET scan is monitoring delivery of target cancer therapy.


Positron Emission Tomography Neuroendocrine Tumor Invasive Lobular Carcinoma 67Gallium Scintigraphy Bone Marrow Disease 
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For Further Reading

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    Fischer B, Lassen U, Mortensen J, Larsen S, Loft A, Bertelsen A, et al. Preoperative staging of lung cancer with PET-CT. N Engl J Med. 2009;361:32–9.PubMedCrossRefGoogle Scholar
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    Kato H, Miyazaki T, Nakajima M, Takita J, Kimura H, Faried A, et al. The incremental effect of positron emission tomography on diagnostic accuracy in the initial staging of esophageal carcinoma. Cancer. 2005;103:148–56.PubMedCrossRefGoogle Scholar
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    Rohren EM, Lowe VJ. Update in PET imaging of nonsmall cell lung cancer. Semin Nucl Med. 2004;34:134–53.PubMedCrossRefGoogle Scholar

Copyright information

© Springer India 2015

Authors and Affiliations

  1. 1.Nuclear MedicineUtkal Institute of Medical SciencesBhubaneswarIndia

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