Comparison of PET-CT with PET-MRI

  • Birendra Kishore Das


Hybrid imaging with positron emission tomography is an evolving technology. The idea to combine PET with CT was made in the early 1990s. A Swiss oncology surgeon suggested adding something useful such as a CT scanner that would provide anatomical information more familiar to surgeons at that time. Thus, the concept of PET-CT was born in 1991, in which the components of a CT scanner would be mounted in the gaps between the banks of BGO block detectors. However, it was soon evident from that such a concept would not be feasible owing to the density of x-ray components mounted on the rotating support. Thus, it took 7 years more before the first prototype combined PET-CT scanner was completed, installed, and became operational in 1998. The coregistered anatomy localized functional abnormalities and clarified equivocal situations, thus improving the accuracy and confidence of the scan interpretation. The use of a rapidly acquired, low-noise CT scan in place of a lengthy conventional PET transmission scan also reduced the overall scan duration. Positron emission tomography/computed tomography (PET-CT) is now established as the imaging modality of choice in many clinical conditions, particularly in oncology.


Metabolic Tumor Volume Hybrid Imaging Soft Tissue Contrast Characterize Liver Lesion Simultaneous Data Acquisition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

For Further Reading

  1. 1.
    Pace L, Nicolai E, Luongo A, Aiello M, Catalano OA, Soricelli A, Salvatore M. Comparison of whole-body PET-CT and PET/MRI in breast cancer patients: lesion detection and quantitation of 18F-deoxyglucose uptake in lesions and in normal organ tissues. Eur J Radiol. 2014;83(2):289–96. doi: 10.1016/j.ejrad.2013.11.002. Epub 2013 Nov 23.PubMedCrossRefGoogle Scholar
  2. 2.
    Townsend DW. Dual-modality imaging: combining anatomy and function. J Nucl Med. 2008;49:938–55.PubMedCrossRefGoogle Scholar
  3. 3.
    von Schulthess GK, Schlemmer HP. A look ahead: PET/MR versus PET-CT. Eur J Nucl Med Mol Imaging. 2009;36 Suppl 1:S3–9.CrossRefGoogle Scholar

Copyright information

© Springer India 2015

Authors and Affiliations

  1. 1.Nuclear MedicineUtkal Institute of Medical SciencesBhubaneswarIndia

Personalised recommendations