Role of PET in Coronary Artery Disease



The use of positron-emitting radionuclides, especially 18 F labeled fluorodeoxy glucose (18 F-FDG), has increased recently due to its role in oncology. This has paved the way to look for other uses for these agents. The use of positron emission tomography (PET) as a noninvasive tool for imaging the heart in coronary artery disease to look for perfusion defects and viability has already been established. This has helped us to know the extent of myocardial blood flow, the metabolic changes occurring in the myocardium, and changes in the cardiac autonomic innervations in various pathological conditions.


Positron Emission Tomography Myocardial Perfusion Myocardial Blood Flow Coronary Flow Reserve Positron Emission Tomography Tracer 
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For Further Reading

  1. 1.
    Bateman TM, Heller GV, McGhie AI, et al. Diagnostic accuracy of rest/stress ECG-gated Rb-82 myocardial perfusion PET: comparison with ECG-gated Tc-99 m sestamibi SPECT. J Nucl Cardiol. 2006;13:24–33. PubMed: 16464714.PubMedCrossRefGoogle Scholar
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    Di Carli MF, Hachamovitch R. New technology for noninvasive evaluation of coronary artery disease. Circulation. 2007;115:1464–80.PubMedCrossRefGoogle Scholar
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    Lortie M, Beanlands RS, Yoshinaga K, Klein R, Dasilva JN, de Kemp RA. Quantification of myocardial blood flow with 82Rb dynamic PET imaging. Eur J Nucl Med Mol Imaging. 2007;34:1765–74.PubMedCrossRefGoogle Scholar
  4. 4.
    Machac J. Cardiac positron emission tomography imaging. Semin Nucl Med. 2005;35:17–36.PubMedCrossRefGoogle Scholar

Copyright information

© Springer India 2015

Authors and Affiliations

  1. 1.Department of Nuclear Medicine and PETSanjay Gandhi Postgraduate Institute of Medical SciencesLucknowIndia
  2. 2.Department of Nuclear MedicineSanjay Gandhi Postgraduate Institute of Medical SciencesLucknowIndia

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