Introduction to Oxidative Stress

  • Mohinder Bansal
  • Naveen Kaushal


Oxygen as an essential element is critical for energy production and existence of all organisms on earth. However, there are potentially damaging effects also associated with it leading to production of oxygen centered free radicals. These radicals are highly reactive and can cause damage to various biomolecules. Presence of a physiological antioxidant defense system keeps these free radicals in check. Any imbalance in the levels of free radicals or reactive oxygen species (ROS) leads to oxidative stress in the body and may culminate in various patho-physiological conditions. In this chapter we have systematically provided details about the sources of free radicals, their types, their biomarkers and physiological significance.


Reactive Oxygen Species Nitric Oxide Reactive Oxygen Species Production Superoxide Radical Xanthine Oxidase 


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Copyright information

© Springer India 2014

Authors and Affiliations

  • Mohinder Bansal
    • 1
  • Naveen Kaushal
    • 1
  1. 1.Department of BiophysicsPanjab UniversityChandigarhIndia

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