Pharmacotherapy of CVI
Pharmacotherapy of chronic venous insufficiency (CVI) and varicose veins is an area which cannot claim significant progress. Several drugs are used to control the symptoms of chronic venous disorders and promote healing of venous ulcers. None of them are effective in altering the course of the disease. The wonder drug in this arena would be one that can completely reverse the underlying molecular pathology of this disease.
KeywordsUlcer Healing Varicose Vein Ginkgo Extract Venous Ulcer Chronic Venous Insufficiency
- 2.Coleridge Smith PD. Drug treatment of varicose veins, venous edema and ulcers. In: Gloviczki P, editor. Handbook of venous disorders: guidelines of the American Venous Forum. 3rd ed. London: Hodder Arnold; 2009. p. 359–65.Google Scholar
- 8.Royal College of Nursing. Clinical practice guidelines: the nursing management of patients with venous leg ulcers. London: Royal College of Nursing; 2006. Publication Code: 003020. ISBN 1-904114-22-9.Google Scholar
- 9.Mortimer PS, Burnand KG, Neumann HAM. Diseases of veins and arteries: leg ulcers. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook’s text book of dermatology. 8th ed. Oxford: Wileyblackwell; 2010. p. 2270.Google Scholar
- 10.Belcaro G, Marelli C. Treatment of venous lipodermatosclerosis and ulceration in venous hypertension by elastic compression and fibrinolytic enhancement with defibrotide. Phlebology. 1989;4(2):91–106.Google Scholar
- 15.Glynn RJ, Danielson E, Fonseca FAH, Genest J, Gotto Jr AM, Kastelein JJP, Koenig W, Libby P, Lorenzatti AJ, Mac Fadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Ridker PM. A randomised trial of rosuvastatin in the prevention of venous thromboembolism. N Engl J Med. 2009;360:1851–61.PubMedCrossRefPubMedCentralGoogle Scholar