Quorum Sensing in Escherichia coli: Interkingdom, Inter- and Intraspecies Dialogues, and a Suicide-Inducing Peptide

  • Bloom-Ackermann Zohar
  • Ilana Kolodkin-Gal


An emerging theme in microbiology is the ability of bacteria to communicate with one another via quorum-sensing signal molecules (Bassler and Losick, Cell 125:237–246, 2006; Camilli and Bassler, Science 311:1113–1116, 2006; Fuqua et al., Annu Rev Microbiol 50:727–751, 1996; Waters and Bassler, Annu Rev Cell Dev Biol 21:319–346, 2005). Quorum sensing provides a mechanism for bacteria to monitor one another’s presence and to modulate gene expression in response to population density. In the simplest scenario, accumulation of a threshold autoinducer concentration, which is correlated with increasing population density, initiates a signal transduction cascade that culminates in a population-wide alteration in gene expression. Our text brought here is highlighting the recent development in the study of quorum-sensing behaviors in E. coli. This bacterium intriguingly integrates self-produced quorum-sensing signals as well as signals produced by epithelial cells and neighbor gut bacteria.


Acid Resistance luxS Mutant LuxR Homolog LuxI Homolog Indole Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer India 2015

Authors and Affiliations

  1. 1.Department of Molecular GeneticsWeizmann Institute of ScienceRehovotIsrael

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