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Biotechnological Applications of Quorum-Sensing Inhibitors in Aquacultures

  • Faseela Hamza
  • Ameeta Ravi Kumar
  • Smita Zinjarde
Chapter

Abstract

Aquaculture is an important food production sector that is estimated to increase rapidly in the future. This segment is challenged with issues such as disease outbreaks and emergence of antibiotic-resistant pathogenic strains. In most of the aquatic pathogens, the importance of quorum sensing for survival and development of virulence factors is well-documented. An understanding on the molecular basis of this phenomenon has led to the development of new strategies for disease control and a search for molecules interfering with related processes. This chapter briefly describes the quorum-sensing systems prevalent in the major aquaculture and aquatic pathogens Vibrio harveyi and Pseudomonas aeruginosa, details the structural features of quorum-sensing inhibitors (QSIs) of biological and chemical origin, discusses their mode of action, and highlights their use as alternative control agents. Such QSIs may in the future prove to be effective and sustainable alternatives and help in replacing the currently used antibiotics or sanitizers to some extent.

Keywords

Quorum Sense Boronic Acid Kojic Acid Quorum Sense System Vibrio Species 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

All authors thank University Grants Commission for funding under UPE Phase II. FH thanks DST, India, for financial support under WOS-B scheme.

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Copyright information

© Springer India 2015

Authors and Affiliations

  • Faseela Hamza
    • 1
  • Ameeta Ravi Kumar
    • 1
  • Smita Zinjarde
    • 1
  1. 1.Institute of Bioinformatics and BiotechnologyUniversity of PunePuneIndia

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