Herbs for Mitigating High Altitude Maladies

  • Richa Rathor
  • Priyanka Sharma
  • Geetha Suryakumar
  • Asheesh Gupta
  • Gidugu Himashree
  • Gopinath Bhaumik


A large number of armed forces are deployed at mountainous regions of the country. Nevertheless, a significant fall in work efficiency and physical performance is observed at high altitude. In view of the above, there is an essential requisite for identification of pharmacotherapeutic interventions (herbal, dietary, or chemical agents) to boost endurance and performance and to mitigate cold injuries and promote wound healing under stressful conditions. In the last few decades, DIPAS has extensively worked on this area, and this article summarizes the studies conducted under the aegis of DIPAS to ascertain the role of herbs in mitigating high-altitude maladies. Extensive scientific studies at DIPAS have focused on the development of adaptogens, herbal formulations which help to enhance nonspecific resistance to stress and improve physical performance. In this context, three herbal preparations such as Composite Indian Herbal Preparation-I (CIHP-I), Composite Indian Herbal Preparation II (CIHP-II), and “DIP-91” have been developed with significant antistress as well as adaptogenic activity. A herbal wound healer named “HERBO HEALER” is a product which possesses antioxidant, antibacterial activity and wound-healing activity in both acute as well as chronic wounds. DIPAS has also formulated a cream named “ALOCAL,” which is having a promising role against cold injury. A hypolipidemic agent named “DIP-LIP” was also developed that possessed antiatherogenic, cardioprotective activities and vasorelaxation activity.

Conclusively, herbs possess a wide range of therapeutic effects, and through systematic scientific investigations using various animal models and clinical trials, research at DIPAS has translated this knowledge into products for protection against high-altitude maladies and also for enhancing performance under stressful conditions.


Wound Healing Acute Mountain Sickness Cold Injury Herbal Formulation Wound Healing Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer India 2014

Authors and Affiliations

  • Richa Rathor
    • 1
  • Priyanka Sharma
    • 1
  • Geetha Suryakumar
    • 1
  • Asheesh Gupta
    • 1
  • Gidugu Himashree
    • 2
  • Gopinath Bhaumik
    • 1
  1. 1.Defence Institute of Physiology and Allied Sciences (DIPAS), DRDODelhiIndia
  2. 2.High Altitude Physiology GroupDefence Institute of Physiology and Allied Sciences (DIPAS)Timarpur, DelhiIndia

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