Toxic Effects and Remedy

  • Shabnum Nabi


The LD50 of methylmercury in rodents treated orally is usually 10–40 mg/kg BW. Methylmercury is also considered to be corrosive at high doses (WHO 2000). Alterations in various serum and urine biochemical parameters within 72 h after dosing were observed in male rats given mercury as a single oral dose (total mercury, 3.96 mg/kg body weight; methylmercury, 0.047 mg/kg body weight) in boiled whale blubber. The activity of serum lactate dehydrogenase was increased twofold, and there were significant increases in urinary volume and activity of N-acetyl-beta-D-glucosaminidase and albumin compared with the control group, which received total mercury in a single dose of 0.4 μg/kg body weight (Endo et al. 2003).


Amyotrophic Lateral Sclerosis Total Mercury Mercury Vapor Elemental Mercury Mercury Poisoning 
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© Springer India 2014

Authors and Affiliations

  • Shabnum Nabi
    • 1
  1. 1.Interdisciplinary Brain Research Centre (IBRC) Jawaharlal Nehru Medical CollegeAligarh Muslim UniversityAligarhIndia

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