Abstract
Surface Plasmon Resonance (SPR)-based biosensing systems have become very popular among biologists and biochemists due to their ability to sense biomolecular interaction kinetics. It can be easily surmised that such systems may be of great use in diagnostic applications as well. However, the principal impediment to wide-scale deployment of these devices is the cost of the instrument. This effort to develop a low cost, widely deployable instrument was born out of a desire to initially popularize this instrument and technique among colleges and universities with budget constraints and move toward developing diagnostic applications on this platform. A low-cost device with significant sensitivity was developed, and this chapter describes the development on this front.
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Acknowledgments
The development of the SPR system was partially supported by the NPMASS project “A lab on chip of Cardiac Diagnostics”. The authors also acknowledge the contribution of a large number of students toward this development viz. Kanak Mhatre, Joaquim Ignetious Monteiro, Rahul Bharadwaj, Vamsi Ravali, Gauri Shukla, Tanneru Kumaraswami, and Dhananjay Patil.
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Mukherji, S., Hossain, M.I., Kundu, T., Chandratre, D. (2014). Development of a Surface Plasmon Resonance-Based Biosensing System. In: Vinoy, K., Ananthasuresh, G., Pratap, R., Krupanidhi, S. (eds) Micro and Smart Devices and Systems. Springer Tracts in Mechanical Engineering. Springer, New Delhi. https://doi.org/10.1007/978-81-322-1913-2_4
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DOI: https://doi.org/10.1007/978-81-322-1913-2_4
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