Abnormal uterine bleeding is one of the most common problems a woman faces in her reproductive life span, and it accounts for 20 % of visits to the gynecologic clinic. Abnormal uterine bleeding (AUB) is defined as “bleeding from the uterine corpus that is abnormal in regularity, volume, frequency or duration” and accounts for 25 % of all gynecologic procedures . All clinicians dealing with a case of abnormal uterine bleeding face the basic challenge of excluding any genital tract malignancy by formulating a well-organized and logical approach for evaluation of the symptom. Abnormal uterine bleeding is caused by the disruption of normal physiology, anatomical changes in the endometrium, or endometrial malignancy; therefore, the role of detailed history and clinical examination of the pelvis, besides endometrial sampling and imaging studies, forms the backbone of evaluating this condition.
KeywordsEndometrial Cancer Endometrial Carcinoma Endometrial Thickness Endometrial Hyperplasia Endometrial Biopsy
- 8.44 NCG. Heavy menstrual bleeding. London: National Institute for Health and Clinical Excellence; 2007.Google Scholar
- 11.ACOG Committee opinion. Role of transvaginal scan in the evaluation of postmenopausal bleeding. Number 440, Aug 2009.Google Scholar
- 12.Fritz MA, Speroff L. Clinical gynaecologic endocrinology and infertility. 8th ed. Wolters Kluwer/LWW. 2010; p. 605.Google Scholar
- 25.ACOG Committee opinion on tamoxifen and uterine cancer. Number 336, June 2006.Google Scholar