Skip to main content

Surveillance of Uterine Sarcomas

  • Chapter
  • 1164 Accesses

Abstract

Uterine sarcomas are uncommon tumors which constitute 3 % of all uterine malignancies [1]. They are aggressive tumors with a tendency for local and distant spread and hence have a guarded prognosis. These include leiomyosarcomas (LMS), endometrial stromal tumors (ESS), undifferentiated uterine sarcomas (UUS), and pure heterologous sarcomas. Mixed epithelial and mesenchymal tumors are adenosarcomas and carcinosarcomas.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   149.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. D’Angelo E, Prat J. Uterine sarcomas: a review. Gynecol Oncol. 2010;116:131–9.

    Article  PubMed  Google Scholar 

  2. Major F, Blessing J, Silverberg S, Morrow C, Creasman W, Currie J, et al. Prognostic factors in early-stage uterine sarcoma. A Gynecologic Oncology Group study. Cancer. 1993;71 Suppl 4:1702–9.

    Article  CAS  PubMed  Google Scholar 

  3. Ramondetta LM, Bodurka DC, Deavers MT, Jhingran A. Uterine sarcomas. In: Eifel P, editor. Gynecologic cancer, M. D. Anderson cancer care series. New York: Springer; 2006. p. 125–47.

    Chapter  Google Scholar 

  4. Gadducci A. Prognostic factors in uterine sarcoma. Best Pract Res Clin Obstet Gynaecol. 2011;25:783–95.

    Article  PubMed  Google Scholar 

  5. Tavassoli F, Deville P, editors. Pathology & genetics of the tumours of the breast and female genital organs. World Health Organization Classification of Tumours. Lyon: IARC Press; 2003. p. 233–6.

    Google Scholar 

  6. Gadducci A, Sartori E, Landoni F, et al. Endometrial stromal sarcoma: analysis of treatment failures and survival. Gynecol Oncol. 1996;63:247–53.

    Article  CAS  PubMed  Google Scholar 

  7. Gadducci A, Cosio S, Romanini A, et al. The management of patients with uterine sarcoma: a debated clinical challenge. Crit Rev Oncol Hematol. 2008;65:129–42.

    Article  PubMed  Google Scholar 

  8. Trope CG, Abeler VM, Kristensen GB. Diagnosis and treatment of sarcoma of the uterus. A review. Acta Oncol. 2012;51:694–705.

    Article  PubMed  Google Scholar 

  9. Kapp DS, Shin JY, Chan JK. Prognostic factors and survival in 1396 patients with uterine leiomyosarcomas: emphasis on impact of lymphadenectomy and oophorectomy. Cancer. 2008;112:820–30.

    Article  PubMed  Google Scholar 

  10. Blom R, Guerrieri C, Stâl O, et al. Leiomyosarcoma of the uterus: a clinicopathologic, DNA flow cytometric, p53, and mdm-2 analysis of 49 cases. Gynecol Oncol. 1998;68:54–61.

    Article  CAS  PubMed  Google Scholar 

  11. Mayerhofer K, Obermair A, Windbichler G, et al. Leiomyosarcoma of the uterus: a clinicopathologic multicenter study of 71 cases. Gynecol Oncol. 1999;74:196–201.

    Article  CAS  PubMed  Google Scholar 

  12. Leitao MM, Soslow RA, Nonaka D, et al. Tissue microarray immunohistochemical expression of estrogen, progesterone and androgen receptors in uterine leiomyomata and leiomyosarcoma. Cancer. 2004;101:1455–62.

    Article  CAS  PubMed  Google Scholar 

  13. Nordal RR, Kristensen GB, Kaern J, et al. The prognostic significance of surgery, tumor size, malignancy grade, menopausal status, and DNA ploidy in endometrial stromal sarcoma. Gynecol Oncol. 1996;62:254–9.

    Article  CAS  PubMed  Google Scholar 

  14. Sartori E, Bazzurini L, Gadducci A, et al. Carcinosarcoma of the uterus: a clinicopathological multicenter CTF study. Gynecol Oncol. 1997;67:70–5.

    Article  CAS  PubMed  Google Scholar 

  15. Yamada SD, Burger RA, Brewster WR, et al. Pathologic variables and adjuvant therapy as predictors of recurrence and survival for patients with surgically evaluated carcinosarcoma of the uterus. Cancer. 2000;88:2782–6.

    Article  CAS  PubMed  Google Scholar 

  16. Ferguson SE, Tornos C, Hummer A, et al. Prognostic features of surgical stage I uterine carcinosarcoma. Am J Surg Pathol. 2007;31:1653–61.

    Article  PubMed  Google Scholar 

  17. Huang GS, Chiu LG, Gebb JS, et al. Serum CA125 predicts extrauterine disease and survival in uterine carcinosarcoma. Gynecol Oncol. 2007;107:513–7.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  18. Abeler VM, Røyne O, Thoresen S, et al. Uterine sarcomas in Norway. A histopathological and prognostic survey of a total population from 1970 to 2000 including 419 patients. Histopathology. 2009;54:355–64.

    Article  PubMed  Google Scholar 

  19. Gadducci A, Sartori E, Landoni F, et al. The prognostic relevance of histological type in uterine sarcomas: a Cooperation Task Force (CTF) multivariate analysis of 249 cases. Eur J Gynaecol Oncol. 2002;23:295–9.

    CAS  PubMed  Google Scholar 

  20. Koh WJ, Greer BE, Abu-Rustum NR, et al. Uterine neoplasms, version 1.2014. J Natl Compr Canc Netw. 2014;12(2):248–80.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shalini Rajaram MD, FAMS .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer India

About this chapter

Cite this chapter

Kumar, N., Rajaram, S. (2015). Surveillance of Uterine Sarcomas. In: Rajaram, S., K, C., Maheshwari, A. (eds) Uterine Cancer. Springer, New Delhi. https://doi.org/10.1007/978-81-322-1892-0_34

Download citation

  • DOI: https://doi.org/10.1007/978-81-322-1892-0_34

  • Publisher Name: Springer, New Delhi

  • Print ISBN: 978-81-322-1891-3

  • Online ISBN: 978-81-322-1892-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics