Uterine Cancer pp 369-379 | Cite as

Role of Systemic Therapy in the Management of Uterine Sarcomas

  • Jyoti Bajpai
  • Susan Deepa


Uterine sarcomas are a heterogenous group of rare neoplasms with varied histology, clinical behaviour and chemosensitivity [1]. The broad terminology of uterine sarcomas encompasses leiomyosarcoma [LMS], carcinosarcoma, endometrial stromal sarcoma (ESS), and undifferentiated sarcomas [2, 3]. Uterine sarcomas generally have an aggressive clinical behavior, with a tendency for local recurrence and distant spread. Despite high risk of recurrence, the role of adjuvant therapy in uterine sarcoma is still controversial. A phase III randomized trial comparing adjuvant chemotherapy (ACT) to a no-chemotherapy control group is needed to give a final verdict to the management strategy. This chapter will address current management strategies.


Overall Survival Gynecologic Oncology Group Uterine Sarcoma Endometrial Stromal Sarcoma Undifferentiated Sarcoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material


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© Springer India 2015

Authors and Affiliations

  1. 1.Department of Medical OncologyTata Memorial HospitalMumbaiIndia

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