Hereditary Cancers of the Endometrium: HNPCC Syndrome and Beyond

  • Anupama Rajanbabu
  • Walter H. Gotlieb


The incidence of endometrial cancer is increasing worldwide [1]. Identifying women who are at increased risk of endometrial cancer can help in the early diagnosis and prevention of the disease. Obesity, early menarche and late menopause, tamoxifen use, hereditary factors like hereditary nonpolyposis colorectal carcinoma (HNPCC) syndrome, diabetes mellitus, systemic hypertension, etc. are some of the high-risk factors associated with carcinoma of the endometrium. The lifetime risk for endometrial cancer increases from 2.6 % to about 60 % in HNPCC syndrome [2].


Endometrial Cancer Lynch Syndrome Endometrial Carcinoma Endometrial Cancer Patient Endometrioid Adenocarcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer India 2015

Authors and Affiliations

  1. 1.Department of Gynecological OncologyAmrita Institute of Medical Sciences and Research Centre, Amrita VishwavidyapeethamKochiIndia
  2. 2.Division of Surgical and Gynecologic OncologyJewish General Hospital, McGill UniversityMontrealCanada

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