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Sentinel Node Evaluation in Endometrial Cancer

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Abstract

Comprehensive surgical staging is meant to serve as a guide to appropriate postoperative adjuvant therapy for endometrial cancer. However, lymphadenectomy is not without complications and has been associated with increased risk of blood vessel and nerve damage,lymphedema, and lymphocyst formation. In addition, some have questioned the therapeutic value of systematic lymphadenectomy. Two recent, large randomized control trials revealed that systematic lymphadenectomy was not associated with improved overall recurrence or survival rates [2–4].However, the methodologies of both these studies were the subject of criticism [5, 6], and thus,not everyone is quite ready to discontinue lymphadenectomies. Recently, sentinel lymph node (SLN) mapping has emerged as a promising compromise to the ongoing debate.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, McGill University, Montreal, QC, Canada

    Jeffrey Howe MD

  2. Division of Surgical and Gynecologic Oncology, Jewish General Hospital, McGill University, 3755 Cote Ste Catherine Road, Room E716, Montreal, QC, Canada

    Walter H. Gotlieb MD, PhD

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  1. Jeffrey Howe MD
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  2. Walter H. Gotlieb MD, PhD
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Correspondence to Walter H. Gotlieb MD, PhD .

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Editors and Affiliations

  1. Obstetrics and Gynecology, University College of Medical Sciences, New Delhi, India

    Shalini Rajaram

  2. Surgical &Gynec Oncology, Lakeshore & Welcare Hospitals, Kochi, Kerala, India

    Chitrathara K

  3. Gynec Onclogy, Tata Memorial Hospital, Mumbai, India

    Amita Maheshwari

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Howe, J., Gotlieb, W.H. (2015). Sentinel Node Evaluation in Endometrial Cancer. In: Rajaram, S., K, C., Maheshwari, A. (eds) Uterine Cancer. Springer, New Delhi. https://doi.org/10.1007/978-81-322-1892-0_15

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  • DOI: https://doi.org/10.1007/978-81-322-1892-0_15

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