Uterine Cancer pp 179-191 | Cite as

Sentinel Node Evaluation in Endometrial Cancer

  • Jeffrey Howe
  • Walter H. Gotlieb


Comprehensive surgical staging is meant to serve as a guide to appropriate postoperative adjuvant therapy for endometrial cancer. However, lymphadenectomy is not without complications and has been associated with increased risk of blood vessel and nerve damage,lymphedema, and lymphocyst formation. In addition, some have questioned the therapeutic value of systematic lymphadenectomy. Two recent, large randomized control trials revealed that systematic lymphadenectomy was not associated with improved overall recurrence or survival rates [2–4].However, the methodologies of both these studies were the subject of criticism [5, 6], and thus,not everyone is quite ready to discontinue lymphadenectomies. Recently, sentinel lymph node (SLN) mapping has emerged as a promising compromise to the ongoing debate.


Sentinel Lymph Node Endometrial Cancer Myometrial Invasion Isolate Tumor Cell Sentinel Lymph Node Mapping 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer India 2015

Authors and Affiliations

  1. 1.Department of Obstetrics and GynecologyMcGill UniversityMontrealCanada
  2. 2.Division of Surgical and Gynecologic OncologyJewish General Hospital, McGill UniversityMontrealCanada

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