Abstract
Herpetic infections of the cornea are a common cause of ocular morbidity. Appropriate management of these infections go a long way in reducing their chronic sequelae. The Herpetic Eye Disease Study (HEDS) has given us reasonable guidelines to manage HSV keratitis. End-stage sequelae might require corneal transplant or in rare cases keratoprosthesis to restore vision.
Herpes zoster primarily occurs in the elderly or immune compromised patients and affects 10–25 % of all zoster dermatitis patients and often results in chronic ocular inflammation, visual loss, and pain.
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References
Liesegang TJ, Melton III LJ, Dally PJ, Llstrup DM. Epidemiology of ocular herpes simplex. Incidence in Rochester Minn, 1950 through 1982. Arch Ophthalmol. 1989;107:1155–9.
Liesegang TJ, Melton III LJ, Dally PJ, Llstrup DM. Epidemiology of ocular herpes simplex. Natural history in Rochester Minn, 1950 through 1982. Arch Ophthalmol. 1989;107:1160–5.
Pavan-Langston D, et al. In: Foster S, Azar D, Dohlman C, editors. Viral disease of the ocular anterior segment: basic science and clinical disease. Philadelphia: Lippincott, Williams & Wilkins; 2005. p. 297–397.
Egerer U-D, Stary A. Erosive-ulcerative herpes simplex blepharitis. Arch Ophthalmol. 1980;98:1760.
Foster Jr WJ, Kraus MD, Custer PL. Herpes simplex virus dacryoadenitis in an immunocompromised patient. Arch Ophthalmol. 2003;121:911–3.
Holland EJ, Schwartz GS, Neff KD. Herpes simplex keratitis chapter 79 In: Krachmer, Cornea 3rd edition, Elseiver 2011, Volume 1 chapter 79, 953–984.
Coepland Jr R, Afshari NA. Viral keratitis. Chapter 23 in principles and practice of Cornea. vol 1, 1st ed. 2013: p. 265–83.
Pavan-Langston D. In: Albert D, Jakobiec F, editors. Viral disease of the cornea and external eye. Philadelphia: WB Saunders; 2000. p. 846–93.
Barron BA, Gee L, Hauck WW, et al. Herpetic eye disease study. A controlled trial of oral acyclovir for herpes simplex stromal keratitis. Ophthalmology. 1994;101:1871–82.
HEDS. Oral acyclovir for herpes simplex virus eye disease. Effect on prevention of epithelial keratitis and stromal keratitis. Herpetic Eye Disease Study Group. Arch Ophthalmol. 2000;118:1030–6.
HEDS. A controlled trial of oral acyclovir for the prevention of stromal keratitis or iritis in patients with herpes simplex virus epithelial keratitis. The epithelial keratitis trial. The Herpetic Eye Disease Study Group. Arch Ophthalmol. 1997;115:703–12.
HEDS. Acyclovir for the prevention of recurrent herpes simplex virus eye disease. Herpetic Eye Disease Study Group. N Engl J Med. 1998;339:300–6.
Khan BF, Pavan-Langston D. Clinical manifestations and treatment modalities in herpes simplex virus of the ocular anterior segment. Int Ophthalmol Clin. 2004;44:103–33.
Simon AL, Pavan-Langston D. Long-term oral acyclovir therapy. Effect on recurrent infectious herpes simplex keratitis in patients with and without grafts. Ophthalmology. 1996;103:1399–405.
van Rooij J, Rijneveld WJ, Remeijer L, et al. Effect of oral acyclovir after penetrating keratoplasty for herpetic keratitis: a placebo controlled multicenter trial. Ophthalmology. 2003;110:1916.
Scott G, Stones DU, James C. Evidence-based treatment of herpes simplex virus keratitis: a systematic review. Ocul Surf. 2007;5(3):240–50.
Langston RH, Pavan-Langston D. Penetrating keratoplasty for herpetic keratitis: decision-making and management. Int Ophthalmol Clin. 1975;15:125–40.
Kahn B, Aqualvella J, Harissi-Dagher M, et al. The Boston keratoprosthesis in herpetic keratitis. Arch Ophthlamol. 2007;125:745–9. Wilson FI. In: Tabbara K, Hyndiuk R, editors. Varicella and Herpes zoster ophthalmicus. Boston: Little, Brown; 1996. p. 387–400.
Liesegang TJ. Herpes zoster ophthalmicus. Natural history, risk factors, clinical presentation, and morbidity. Ophthalmology. 2008;115:S3–12.
Liesegang TJ. Diagnosis and therapy of herpes zoster ophthalmicus. Ophthalmology. 1991;98:1216–29.
Lee WB, Liesegang TJ. Herpes zoster keratitis. In: Krachmer, Cornea 3rd edition, Elseiver 2011: Volume 1, chapter 80, 985–1000.
Herbort CP. Acyclovir in herpes zoster ophthalmicus. Br J Ophthalmol. 1991;75(9):542–6.
Hoang-Xuan T, Büchi ER, Herbort CP, Denis J, Frot P, Thénault S, Pouliquen Y. Oral acyclovir for herpes zoster ophthalmicus. Ophthalmology. 1992;99(7):1062–70.
Colin J, Prisant O, Cochener B, Lescale O, Rolland B, Hoang-Xuan T. Comparison of the efficacy and safety of valaciclovir and acyclovir for the treatment of herpes zoster ophthalmicus. Ophthalmology. 2000;107(8):1507–11.
Soong HK, Schwartz AE, Meyer RF, Sugar A. Penetrating keratoplasty for corneal scarring due to herpes zoster ophthalmicus. Br J Ophthalmol. 1989;73:19–21.
Pavan-Langston D, Dohman CH. Boston keratoprosthesis treatment of herpes zoster neurotrophic keratopathy. Ophthalmology. 2008;115:S21–3.
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Srinivasan, B., Iyer, G., Agarwal, M., Agarwal, S. (2017). Viral Keratitis. In: Mukherjee, B., Yuen, H. (eds) Emergencies of the Orbit and Adnexa. Springer, New Delhi. https://doi.org/10.1007/978-81-322-1807-4_37
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