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Minimal Stimulation and Natural Cycle In Vitro Fertilization pp 87–94Cite as

Vitrification Is the Keystone to Minimal Stimulation IVF

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Abstract

Minimal stimulation in vitro fertilization (IVF) has several benefits over conventional IVF protocols, including less medication, fewer injections, and producing fewer but better quality eggs. The use of Clomiphene citrate in minimal stimulation IVF protocols has a negative impact on the endometrium. Cryopreserved embryo transfers with this protocol have yielded much higher pregnancy rates compared to fresh transfers. Minimal stimulation cycle with a remote embryo transfer (rET) is a viable option only when it is combined with an efficient embryo cryopreservation program. The recent use of the vitrification technique has shown a higher embryo survival rate, compared with slow freezing, resulting in significantly higher implantation and pregnancy rates per transfer. Therefore, the use of elective cryopreservation of viable embryos could be an alternative to avoid the deleterious effects of the stimulation cycles on embryo–endometrium synchrony.

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Author information

Authors and Affiliations

  1. Department of Assisted Reproduction, Rotunda – The Center for Human Reproduction, 36, Turner Road, B-Wing, 101, Bandra W, Mumbai, Maharashtra, 400 050, India

    Goral Gandhi MSc

  2. Department of Assisted Reproduction, Rotunda-Blue Fertility Clinic & Keyhole Surgery Center, Rotunda – The Center for Human Reproduction, 36, Turner Road, B-Wing, 101, Bandra W, Mumbai, Maharashtra, 400 050, India

    Gautam N. Allahbadia MD, DNB, FNAMS, FCPS, DGO, DFP

Authors
  1. Goral Gandhi MSc
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  2. Gautam N. Allahbadia MD, DNB, FNAMS, FCPS, DGO, DFP
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Correspondence to Goral Gandhi MSc .

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Editors and Affiliations

  1. 1st floor, Rotunda-CHR 36, Mumbai, India

    Gautam N. Allahbadia

  2. Department of Assisted Reproduction, Obstetrics and Gynecology, ICI – Instituto Canario de Infertilidad , Las Palmas de Gran Canaria, Spain

    Markus Nitzschke

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Gandhi, G., Allahbadia, G.N. (2015). Vitrification Is the Keystone to Minimal Stimulation IVF. In: Allahbadia, G., Nitzschke, M. (eds) Minimal Stimulation and Natural Cycle In Vitro Fertilization. Springer, New Delhi. https://doi.org/10.1007/978-81-322-1118-1_11

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  • DOI: https://doi.org/10.1007/978-81-322-1118-1_11

  • Publisher Name: Springer, New Delhi

  • Print ISBN: 978-81-322-1117-4

  • Online ISBN: 978-81-322-1118-1

  • eBook Packages: MedicineMedicine (R0)

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