Linkage Map Construction

  • N. Manikanda Boopathi


Genome mapping methods are generally divided into two categories: (1) genetic or linkage mapping and (2) physical mapping. Genetic mapping is based on the use of genetic techniques to construct maps showing the positions of genes and other sequence features on a genome, whereas physical maps are constructed by directly sequencing DNA molecules, and such physical map shows the positions of sequence features, including genes. There is yet another map in genome analysis, which is called as cytogenetic map. It is a genetic term used to describe the visual appearance of a chromosome (known as karyotype) when chromosomes are stained and examined under a microscope. Physical map identifies actual physical position of genes and other DNA elements on the chromosomes and facilitates positional cloning of agronomically important genes and analysing chromosomes and genome structure in detail (refer chapter x for detailed description). This chapter focuses on detailed description of genetic or linkage mapping besides briefly portraying other two types of mapping procedure.


Linkage Group Travel Salesman Problem Recombination Frequency Marker Order Recombination Fraction 
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Further Readings

  1. Bailey NTJ (1961) Introduction to the mathematical theory of genetic linkage. Oxford University Press, LondonGoogle Scholar
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  5. Wu R, Gallo-Meagher M, Littell RC, Zeng Z (2001) General polyploid model for analyzing gene segregation in outcrossing tetraploid species. Genetics 159:869–882PubMedGoogle Scholar

Copyright information

© Springer India 2013

Authors and Affiliations

  1. 1.Plant Molecular Biology & BioinformaticsTamil Nadu Agricultural UniversityCoimbatoreIndia

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