ACE Inhibition and Antioxidant Activities of Enzymatically Synthesised Aminoacyl Esters and Glycosides

  • Soundar Divakar


Since most of the ACE inhibitory drugs are peptides, this chapter deals with exploration of ACE inhibitory activities for some enzymatically synthesised l-alanyl, l-valyl, l-leucyl, l-isoleucyl, l-proline, l-phenylalanine, l-tryptophan and l-histidine esters of carbohydrates and glycosides of n-octanol, phenolic glycosides of guaiacol, eugenol, curcumin, vanillin, N-vanillyl-nonanamide, dl-dopa, dopamine and vitamin glycosides of retinol, thiamin, riboflavin, pyridoxine, ergocalciferol, cholecalciferol and α-tocopherol. A few glycosides were also tested for antioxidant activities. These results exhibiting both the phenolic and vitamin glycosides holding promising potential as antioxidants and ACE inhibitors are discussed in terms of structure–function relationship between these compounds and those of the commercially known inhibitors.


Antioxidant Activity Phenolic Glycoside Amino Acid Ester Butylate Hydroxy Anisole Carbohydrate Molecule 
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Copyright information

© Springer India 2013

Authors and Affiliations

  1. 1.Central Food Technological Research InstituteMysoreIndia

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