Finding the Current Best Evidence

  • Kameshwar Prasad


Once your question is well formulated, you need to find the current best evidence to answer the question. To do this efficiently, you may do two things: one, to ask a colleague, and two, to search for evidence. The colleague may guide you to the latest and best evidence or give you some information to facilitate your search. In any case, I think it is good to search some online sources so that you don’t miss a recent article. A third source can be the company representatives, who come to inform you of their newer products and claim their (products’) superiority or effectiveness. You may ask them to bring reprint of original articles to substantiate their claim.


MeSH Term Related Article Online Search Partial List Online Source 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    McKibbon KA, Richardson WS, Walker DC. Finding answers to well built clinical questions. Evid Based Med. 1999;6:164–7.Google Scholar
  2. 2.
    Haynes RB, Wilczynski N, McKibbon KA, et al. Developing optimal search strategies for detecting clinically sound studies in MEDLINE. J Am Med Inform Assoc. 1994;1:447–58.PubMedCrossRefGoogle Scholar

Further Reading

  1. Greenhalgh T. How to read a paper: the Medline database. BMJ. 1997;315:180–3.PubMedCrossRefGoogle Scholar
  2. Guyatt G, Rennie D, editors. User’s guides to the medical literature: a manual for evidence-based clinical practice. Chicago: AMA Press; 2002. ( Scholar
  3. Wilczynski NL, Walker CJ, McKibbon KA, Haynes RB. Assessment of methodologic search filters in MEDLINE. Proc Annu Symp Comput Appl Med Care. 1994;17:601–5.Google Scholar

Copyright information

© Springer India 2014

Authors and Affiliations

  • Kameshwar Prasad
    • 1
  1. 1.Department of Neurology Neurosciences Centre, and Clinical Epidemiology UnitAll India Institute of Medical SciencesNew Delhi DelhiIndia

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