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Prospects in Bioscience: Addressing the Issues pp 411–413Cite as

Lymphocyte Teamwork in Tumor Rejection

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Abstract

Immune responsiveness depends on a complex interplay between the elements of innate and adaptive immunity. Several recent studies in various models of immune rejection, including ours in a mouse tumor model, yield new insights into the adaptive control of innate effector functions. This chapter provides a discussion of key observations indicating an indispensable T cell help for innate antitumor immunity.

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Acknowledgements

AS is supported by funds from the NIH grants U54 CA091408 (NCI), 5 U54 RR026140-03 (NCRR), 8 U54 MD007593-03 (NIMHD), and 5P50 CA 090949 (NCI).

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Authors and Affiliations

  1. Laboratory of Lymphocyte Function, Department of Biochemistry and Cancer Biology, School of Medicine, Meharry Medical College, Nashville, TN, 37208, USA

    Anil Shanker

  2. Department of Cancer Biology, Vanderbilt-Ingram Comprehensive Cancer Center, Vanderbilt University, Nashville, TN, 37232, USA

    Anil Shanker

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  1. Anil Shanker
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Correspondence to Anil Shanker .

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Editors and Affiliations

  1. , Dept of Biotechnology & Microbiology, Kannur University, Palayad P.O,Thalassery Campus, Kannur, 670661, Kerala, India

    Abdulhameed Sabu

  2. , Dept. of Biotechnology and Microbiology, Kannur University, Palayad P.O, Thalassery Campus, Kannur, 670661, Kerala, India

    Anu Augustine

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© 2012 Springer India

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Shanker, A. (2012). Lymphocyte Teamwork in Tumor Rejection. In: Sabu, A., Augustine, A. (eds) Prospects in Bioscience: Addressing the Issues. Springer, India. https://doi.org/10.1007/978-81-322-0810-5_49

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