Mass Spectroscopy: Herbal Drugs and Fingerprints
The cultivation and wild collection of different accessions of a medicinal plant species from the different regions of the world may differ for the amounts of marker compounds. The MS fingerprints are based on m/z value of molecule, helps to establish the probable structure of compound. Analysis of herbals by MS highlights key signal patterns that characterize the individual species/chemo-type and provide information about quality, which exists at a certain location and adulterant, if any. The therapeutic components present in the herbals, its isolate, and metabolites are determined and quantified with LC–MS, GC–MS, and LC–MS/MS.
KeywordsGlycyrrhizae Radix Botanical Product Angelicae Sinensis Radix Scutellariae Radix Echinacea Species
- 2.Wang Y, Yang L, He Y, Wang H, Welbeck EW, Annie Bligh SW, Wang Z. Characterization of fifty-one flavonoids in a Chinese herbal prescription longdan xiegan decoction by high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry and photodiode array detection. Rapid Commun Mass Spectrom. 2008;22:1767–78.PubMedCrossRefGoogle Scholar
- 7.Patil PS, Shettigar R. An advancement of analytical techniques in herbal research. J Adv Sci Res. 2010;1(1):8–14.Google Scholar
- Hope JL, Prazen BJ, Nilsson EJ, Jack RM, Synovec RE. Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry detection: analysis of amino acid and organic acid trimethylsilyl derivatives, with application to the analysis of metabolites in rye grass samples. Talanta. 2005;65:380–8.PubMedCrossRefGoogle Scholar