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Chemotherapy

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Schistosomes and Schistosomiasis in South Asia

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Abstract

Schistosomiasis is occurring in three clinical forms, namely, urinary, nasal, and hepatic forms. All these forms differ clinically, yet are caused by one or other schistosome species. Therefore, any drug found effective against a schistosome species (so against a clinical form) is used against any other schistosome species, unless proved more effective for a given schistosome species. For instance, therapeutic efficacy of praziquantel is 80–95% in S. haematobium, 60–90% in S. mansoni, and only 60–80% in S. japonicum (WHO 1985). We have no information whether any drug is more effective against a particular Indian schistosome species. Notwithstanding the type of schistosomicide used, the supportive treatment differs as per symptoms and so according to clinical entity.

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References

  • Agrawal MC (1996) Rabbit as a model for schistosomiasis nasale. J Parasitol Appl Biol 5:25–27

    Google Scholar 

  • Agrawal MC (2007) Final report of Emeritus Scientist scheme on “Control of schistosomiasis under field conditions”. ICAR, New Delhi

    Google Scholar 

  • Agrawal MC, Singh KP (2000) Trials of oxamniquine of Schistosoma incognitum infected rabbits. J Vet Parasitol 14:141–143

    Google Scholar 

  • Agrawal MC, Sano M, Mishra A, Solanki PK (1992) Chemotherapeutic trials with praziquantel against Schistosoma incognitum and Hymenolepis spp. in rats. Indian Vet J 69:279–280

    CAS  Google Scholar 

  • Agrawal MC, Borkakoty MR, Das M (1998) Some observations on nasal schistosomiasis (hur-huria) in a village of Assam. Indian Vet J 75:80–81

    Google Scholar 

  • Agrawal MC, George J, Gupta S (1999) Chemotherapeutic trails using Schistosoma incognitum mouse model. J Parasit Dis 23:137–138

    Google Scholar 

  • Agrawal MC, Singh KP, George J, Gupta S (2005) Niclosamide trials on Indoplanorbis exustus and Lymnaea luteola under different conditions. J Parasit Dis 29:53–58

    Google Scholar 

  • Ahluwalia SS (1968) Studies on host parasite relationship and control of Schistosoma incognitum infection of domestic pig with observations on the zoonotic potentialities of the parasite. PhD thesis, Agra University, Agra

    Google Scholar 

  • Ahluwalia SS (1972) Chemotherapy of schistosomiasis incognitum in pig I. Antimony potassium tartrate and antimony sodium tartrate: a note. Indian J Anim Sci 42:1054–1056

    Google Scholar 

  • Ahluwalia SS (1973a) A note on chemotherapy of schistosomiasis incognitum in pigs. 2. Stibophen, Triostam and Astiban. Indian J Anim Sci 43:793–796

    Google Scholar 

  • Ahluwalia SS (1973b) Chemotherapy of schistosomiasis incognitum in pigs. 3 Ambilhar and Miracil-D. Indian J Anim Sci 43:428–434

    CAS  Google Scholar 

  • Alwar VS (1959) Intensive treatment of nasal schistosomiasis in cattle, a preliminary report. Indian Vet J 36:56–65

    Google Scholar 

  • Alwar VS (1962) Further studies on intensive treatment of nasal schistosomiasis in cattle. Indian Vet J 39:33–39

    Google Scholar 

  • Anandan R, Lalitha CM (1979a) Chemotherapeutic trials against nasal schistosomiasis. II. Distribution of Schistosoma nasale worms in the external organs of treated animals. Cheiron 8:212–214

    Google Scholar 

  • Anandan R, Lalitha CM (1979b) Chemotherapeutic trials against nasal schistosomiasis. I. Efficacy of different schistosomicides. Cheiron 8:187–192

    Google Scholar 

  • Anandan R, Raja EE (1987) Preliminary trials with praziquantel in Schistosoma nasale infection in sheep and goat. Indian Vet J 64:108–110

    Google Scholar 

  • Banerjee PS, Agrawal MC (1989) Comparative efficacy of faecal and liver examination in determining prevalence of bovine schistosomiasis. J Vet Parasitol 3:157–158

    Google Scholar 

  • Baugh SC (1978) A century of schistosomiasis in India: human and animal. Rev Iber Parasitol 38:435–472

    Google Scholar 

  • Bhalerao GD (1948) Blood-fluke problem in India. Presidential address. In: Proceedings of 35th Indian Science Congress, Patna, pp 1–15

    Google Scholar 

  • Bhatia BB, Rai DN (1976) Clinical trials of four drugs in Schistosoma nasale infection in cattle. Indian J Anim Res 10:43–44

    Google Scholar 

  • Biswas G, Tewari HC (1988) Efficacy of some chemotherapeutic agents against experimental infection of Schistosoma incognitum in mice. Indian Vet J 65:304–306

    CAS  Google Scholar 

  • Chaudhri SS, Sudesh K, Gupta RP (1994) Prevalence of Schistosoma indicum in Haryana and treatment trials in sheep. Indian Vet J 71:291–292

    Google Scholar 

  • Chauhan AS, Srivastava CB, Chauhan BS (1973) Studies on the trematode fauna of India. Part 6 – Digenea: Schistosomatidae. J Zool Soc India 25:83–127

    Google Scholar 

  • Choudhury B (1955) Nasal granuloma in the state of West Bengal: studies on sixty-eight cases. Indian Vet J 31:403–414

    Google Scholar 

  • de Bont J, Dvan A, Vercruysse J, Fransen J, Southgate VR, Rollinson D (1989) The effects of praziquantel on Schistosoma nasale infections in cattle. J Vet Pharmacol Ther 12:455–458

    Article  PubMed  Google Scholar 

  • Doraiswamy KP (1934) Nasal granuloma or nasal schistosomiasis in cattle. Indian Vet J 11:25–32

    Google Scholar 

  • Dutt SC, Chandra R, Muralidharam SRG, Srivastava HD (1963) Chemotherapy of Schistosoma indicum infection in sheep. Ann Biochem Exp Med 23:S439–S446

    Google Scholar 

  • Faust EC, Russell PF (1957) Craig and Faust’s clinical parasitology, 6th edn. Lea & Febiger, Philadelphia

    Google Scholar 

  • Garg R, Kumar RR, Yadav CL, Banerjee PS, Vatsya S (2009) Comparative efficacy of praziquantel and triclabendazole against Schistosoma indicum in naturally infected sheep. J Vet Parasitol 23:155–157

    Google Scholar 

  • Jain J, Agrawal MC, Rao KNP (2000) Effect of praziquantel and closantel treatment on haematology and faecal egg count in experimental porcine schistosomiasis. Indian J Anim Sci 70:823–825

    CAS  Google Scholar 

  • Jain J, Agrawal MC, Rao KNP, Jain NK (2001) Effect of praziquantel on histopathology in experimental porcine schistosomiasis. Indian J Anim Sci 71:631–634

    Google Scholar 

  • Lodha KR, Raisinghani PM, Sharma GD, Pant UV, Arya PL, Vyas UK (1981) Note on an outbreak of ovine pulmonary schistosomiasis in the arids of Rajasthan. Indian J Anim Sci 51:382–385

    Google Scholar 

  • Mohan RN (1948) Nasal schistosomiasis, its control and treatment in West Bengal. Indian Farm 9:332–334

    Google Scholar 

  • Mohanty DN, Mohanty RK, Ray SK, Mohanty KM (1984) A note on Schistosoma spindale infection in cattle and its successful treatment. Livest Advis 9:37–39

    Google Scholar 

  • Muraleedharan K, Rajashekar C (1996) Comparative efficacy of some anthelmintics against nasal schistosomiasis in cattle. Indian Vet J 73:265–269

    CAS  Google Scholar 

  • Muraleedharan K, Kumar P, Alwar VS, Hegde KS (1977) The comparative efficacy of neguvon, Ambilhar and sodium tartrate on nasal schistosomiasis in cattle. Indian Vet J 54:703–708

    CAS  Google Scholar 

  • Naidu P (1921) Infective nasal granuloma or snoring disease of cattle. Madras Vet J 10:2–6

    Google Scholar 

  • Naik KN (1942) Experiment on the control of nasal granuloma. Indian J Vet Sci Anim Husb 12:150–159

    Google Scholar 

  • Ottalwar R (1999) Studies on prevalence and chemotherapy of nasal schistosomosis in bovine of Durg area (Chattisgarh). MVSc thesis, Indra Gandhi Krishi Vishwa Vidyalaya, Raipur

    Google Scholar 

  • Patra BN, Murty BK (1955) Nasal granuloma in cattle: some observations from mass treatment undertaken in Balimi, Orissa. Indian Vet J 32:148–150

    Google Scholar 

  • Rahman SA, Sano M, Jagannath MS, Prabhakar KS, D’Souza PE, Prem G (1988) Efficacy of praziquantel against Schistosoma nasale infection in cattle. Trop Anim Health Prod 20:19–22

    Article  PubMed  CAS  Google Scholar 

  • Rai DN, Bhatia BB, Hajela SK (1975) Efficacy of Ambilhar (Ciba) in experimental schistosomiasis incognitum in pigs. Indian Vet J 52:860–862

    Google Scholar 

  • Rao NSK, Mudaliar SV (1936) Observation on the treatment of bovine nasal schistosomiasis. Indian J Vet Sci Anim Husb 6:332–345

    Google Scholar 

  • Sanyal PK (2002) Buffalo vis-a-vis Triclabendazole: an example depicting dose rates for Benzimidazole anthelmintics should not be exptrapolated between species. In: Agrawal MC (ed) Remembering Dr S.C.Dutt: the Parasitologist. Department of Parasitology, College of Veterinary Science and Animal Husbandry, Jabalpur

    Google Scholar 

  • Sen MR (1949) Nasal schistosomiasis treatment with tartar emetic. Indian Vet J 25:453–456

    Google Scholar 

  • Shames N, Agrawal MC, Rao KNP (2000) Chemotherapeutic efficacy of praziquantel and closantel in experimental porcine schistosomiasis. Indian J Anim Sci 70:797–800

    CAS  Google Scholar 

  • Shames N, Jain J, Agrawal MC, Rao KNP (2001) Body weight loss in porcine schistosomiasis. Indian Vet J 78:154–156

    Google Scholar 

  • Shrivastava MK (1997) Chemotherapeutic trials in laboratory animals infected with Schistosoma incognitum and S. spindale. MVSc thesis, Jawaharlal Nehru Krishi Vishwa Vidyalaya, Jabalpur

    Google Scholar 

  • Shrivastava MK, Agrawal MC (1999a) Effect of triclabendazole and oxyclozanide on Schistosoma incognitum infection in mouse. Indian Vet J 76:493–496

    CAS  Google Scholar 

  • Shrivastava MK, Agrawal MC (1999b) Doubtful efficacy of lithium antimony thiomalate (Anthiomaline) in schistosomosis. J Vet Parasitol 13:67–68

    Google Scholar 

  • Shrivastava MK, Agrawal MC (1999c) Efficacy of rafoxanide and CDRI compound 81–470 against Schistosoma incognitum in albino mice. Indian J Anim Sci 69:97–99

    CAS  Google Scholar 

  • Singh BK, Agrawal MC (2005) Triclabendazole on bovine hepatic schistosomosis. Indian J Anim Sci 75:654–655

    Google Scholar 

  • Sreeramulu P (1994) Epizootiology of nasal schistosomiasis in bovines in Andhra Pradesh. Indian Vet J 71:1043–1044

    Google Scholar 

  • Srivastava HD (1960) Blood-flukes. Presidential address. In: Proceedings of 47th Indian Science Congress, Part II, Bombay, pp 105–121

    Google Scholar 

  • Upatoom N, Hoerchner F, Leid K (1988) Therapy against Schistosoma spindale infestation in cattle and buffalo. Vet Med Rev 59:171–174

    Google Scholar 

  • Upatoom N, Pholpark M, Srihakim S, Rompopak S, Leidl K, Hoerchner F (1993) Studies on Schistosoma spindale in cattle and buffaloes in the Northeast of Thailand. 2. Trial treatment. Thai J Vet Med 23:107–118

    Google Scholar 

  • WHO (1985) The control of schistosomiasis. Technical report series 728. World Health Organization, Geneva, p 113

    Google Scholar 

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  1. Veterinary College, 3/4, Datt Arcade Phase Three South Civil Lines, Jabalpur, Madhya Pradesh, India

    Mahesh Chandra Agrawal

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  1. Mahesh Chandra Agrawal
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Agrawal, M.C. (2012). Chemotherapy. In: Schistosomes and Schistosomiasis in South Asia. Springer, India. https://doi.org/10.1007/978-81-322-0539-5_9

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