Abstract
The hallmark features of moyamoya disease are a progressive occlusion of bilateral internal carotid arteries and the development of collateral networks to compensate for the reduced cerebral perfusion [1, 2]. Besides these very specific changes, several other conditions can also lead to the chronic cerebral ischemia encountered mainly in younger patients. It thus becomes necessary to evaluate the hemodynamic condition of patients with moyamoya disease in order to understand the pathophysiology of the syndrome and select appropriate treatments for patients individually.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Abbreviations
- CBF:
-
cerebral blood flow
- CBV:
-
cerebral blood volume
- CMRO2 :
-
cerebral metabolic rate for oxygen
- CPP:
-
cerebral perfusion pressure
- CVD:
-
cerebrovascular disease
- MTT:
-
mean vascular transit time
- OEF:
-
oxygen extraction fraction
- PET:
-
positron emission tomography
References
Suzuki J, Takaku A (1969) Cerebrovascular “moyamoya”” disease. Disease showing abnormal netlike vessels in base of brain. Arch Neurol 20:288–299
Matsushima Y (1999) Moyamoya disease. In: Albright A, Pollack I, Adelson P (eds) Principle and practice of pediatric neurosurgery. Thieme, New York, pp 1053–1069
Nariai T, Matsushima Y, Imae S, et al. (2005) Severe haemodynamic stress in selected subtypes of patients with moyamoya disease: a positron emission tomography study. J Neurol Neurosurg Psychiatry 76:663–669
Phelps ME, Hoffman EJ, Mullani NA, et al. (1975) Application of annihilation coincidence detection to transaxial reconstruction tomography. J Nucl Med 16:210–224
Phelps ME, Mazziotta JC (1985) Positron emission tomography: human brain function and biochemistry. Science 228:799–809
Herscovitch P, Markham J, Raichle ME (1983) Brain blood flow measured with intravenous H2 15O. I. Theory and error analysis. J Nucl Med 24:782–789
Kety SS, Schmidt CF (1948) The nitrous oxide method for the quantitative determination of cerebral blood flow in man: theory, procedure and normal values. J Clin Invest 27:476–483
Grubb RL, Jr., Derdeyn CP, Fritsch SM, et al. (1998) Importance of hemodynamic factors in the prognosis of symptomatic carotid occlusion. JAMA 280:1055–1060
Yamauchi H, Fukuyama H, Nagahama Y, et al. (1999) Significance of increased oxygen extraction fraction in five-year prognosis of major cerebral arterial occlusive diseases. J Nucl Med 40:1992–1998
Powers WJ (1991) Cerebral hemodynamics in ischemic cerebrovascular disease. Ann Neurol 29:231–240
Powers WJ, Grubb RL, Jr., Raichle ME (1984) Physiological responses to focal cerebral ischemia in humans. Ann Neurol 16:546–552
Baron JC, Bousser MG, Rey A, et al. (1981) Reversal of focal “Misery-perfusion syndrome” by extra-intracranial arterial bypass in hemodynamic cerebral ischemia. A case study with 15O positron emission tomography. Stroke 12:454–459
Raichle ME, Martin WRW, Herscovitch P, et al. (1983) Brain blood flow measured with intravenous H2 15O. II. Implementation and validation. J Nucl Med 24:790–798
Cherry S, Phelps M (1996) Imaging brain function with positron emission tomography. In: Toga A, Mazziotta J (eds) Brain mapping: the methods. Academic, San Diego, pp 191–221
Kuwabara Y, Ichiya Y, Sasaki M, et al. (1997) Response to hypercapnia in moyamoya disease. Cerebrovascular response to hypercapnia in pediatric and adult patients with moyamoya disease. Stroke 28:701–707
Nariai T, Senda M, Ishii K, et al. (1998) Posthyperventilatory steal response in chronic cerebral hemodynamic stress: a positron emission tomography study. Stroke 29:1281–1292
Derdeyn CP, Videen TO, Simmons NR, et al. (1999) Count-based PET method for predicting ischemic stroke in patients with symptomatic carotid arterial occlusion. Radiology 212:499–506
Zipfel GJ, Sagar J, Miller JP, et al. (2009) Cerebral hemodynamics as a predictor of stroke in adult patients with moyamoya disease: a prospective observational study. Neurosurg Focus 26:E6
Ikezaki K, Matsushima T, Kuwabara Y, et al. (1994) Cerebral circulation and oxygen metabolism in childhood moyamoya disease: a perioperative positron emission tomography study. J Neurosurg 81:843–850
Nariai T, Suzuki R, Matsushima Y, et al. (1994) Surgically induced angiogenesis to compensate for hemodynamic cerebral ischemia. Stroke 25:1014–1021
Tanaka Y, Nariai T, Nagaoka T, et al. (2006) Quantitative evaluation of cerebral hemodynamics in patients with moyamoya disease by dynamic susceptibility contrast magnetic resonance imaging-comparison with positron emission tomography. J Cereb Blood Flow Metab 26:291–300
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer
About this chapter
Cite this chapter
Nariai, T. (2010). Positron Emission Tomography in Moyamoya Disease. In: Cho, BK., Tominaga, T. (eds) Moyamoya Disease Update. Springer, Tokyo. https://doi.org/10.1007/978-4-431-99703-0_29
Download citation
DOI: https://doi.org/10.1007/978-4-431-99703-0_29
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-99702-3
Online ISBN: 978-4-431-99703-0
eBook Packages: MedicineMedicine (R0)