Perfusion Imaging in Moyamoya Disease

  • Jung-Eun Cheon
  • In-One Kim


Moyamoya disease is a chronic, occlusive cerebrovascular disorder involving the distal internal carotid artery and/or the proximal portion of the anterior and middle cerebral arteries (ACAs and MCAs, respectively). Moyamoya disease is characterized by the extensive development of collateral pathways. The first pathway is known as the “basal moyamoya,” and includes an abnormal dilation of the perforating arteries and a true neoangiogenesis around the circle of Willis. Other collateral pathways may occur via pial-to-pial anastomoses from other less compromised territories, particularly the posterior circulation, or in more advanced cases, via a dural-to-pial collateral pathway, which is known as the “vault moyamoya.” These collateral networks seemingly provide an alternative route of cerebral perfusion in moyamoya disease [1–3].


Single Photon Emission Compute Tomography Cerebral Blood Volume Arterial Spin Label Mean Transit Time Compute Tomography Perfusion 
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Copyright information

© Springer 2010

Authors and Affiliations

  1. 1.Department of RadiologySeoul National University Hospital, Seoul National University College of MedicineJongro-guRepublic of Korea

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