Abstract
The two cardinal clinical features of moyamoya disease are ischemic attacks or intracranial hemorrhages. However, the main clinical presentations of moyamoya disease differ substantially between children and adults. Most children with moyamoya disease develop transient ischemic attacks (TIA) or cerebral infarction, whereas about half of the adult patients develop intracranial hemorrhage, and half develop TIA or cerebral infarction, or both [1]. Regarding the ethnic difference, clinical features and the course of moyamoya disease in whites clearly differ from moyamoya disease in Asians in the timing of the onset of vasculopathy and lower rate of hemorrhage [2].
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References
Kuroda S, Houkin K (2008) Moyamoya disease: current concepts and future perspectives. Lancet Neurol 7:1056–1066
Kraemer M, Heienbrok W, Berlit P (2008) Moyamoya disease in Europeans. Stroke 39:3193–3200
Fukui M, Kono S, Sueishi K et al (2000) Moyamoya disease. Neuropathology 20:S61–S64
Mikulis DJ, Krolczyk G, Desal H et al (2005) Preoperative and postoperative mapping of cerebrovascular reactivity in moyamoya disease by using blood oxygen level-dependent magnetic resonance imaging. J Neurosurg 103:347–355
Kim S, Seol HJ, Cho B et al (2004) Moyamoya disease among young patients: its aggressive clinical course and the role of active surgical treatment. Neurosurgery 54:840–846
Suzuki J, Kodama N (1983) Moyamoya disease — a review. Stroke 14:104–109
Irikura K, Miyasaka Y, Kurata I et al (1996) A source of haemorrhage in adult patients with moyamoya disease: the significance of tributaries from the choroidal artery. Acta Neurochir (Wien) 138:1282–1286
Kawaguchi S, Sakaki T, Morimoto T et al (1996) Characteristics of intracranial aneurysms associated with moyamoya disease. A review of 111 cases. Acta Neurochir (Wien) 138:1287–1294
Marushima A, Yanaka K, Matsuki T et al (2006) Subarachnoid hemorrhage not due to ruptured aneurysm in moyamoya disease. J Clin Neurosci 13:146–149
Osanai T, Kuroda S, Nakayama N et al (2008) Moyamoya disease presenting with subarachnoid hemorrhage localized over the frontal cortex: case report. Surg Neurol 69:197–200
Yonekawa Y, Kahn N (2003) Moyamoya disease. Adv Neurol 92:113–118
Manceau E, Giroud M, Dumas R (1997) Moyamoya disease in children. A review of the clinical and radiological features and current treatment. Childs Nerv Syst 13:595–600
Nakase H, Ohnishi H, Touho H et al (1993) Long-term follow-up study of “epileptic type” moyamoya disease in children. Neurol Med Chir (Tokyo) 33:621–624
Kikuta K, Takagi Y, Arakawa Y et al (2006) Absence epilepsy associated with moyamoya disease. Case report. J Neurosurg (4 Suppl Pediatrics) 104:265–268
Moritake K, Handa H, Yonekawa Y et al (1986) Follow-up study on the relationship between age at onset of illness and outcome in patients with moyamoya disease. No Shinkei Geka 14:957–963
Hirano T, Uyama E, Tashima K et al (1998) An atypical case of adult moyamoya disease with initial onset of brain stem ischemia. J Neurol Sci 157:100–104
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Hwang, YS. (2010). Clinical Features of Moyamoya Disease: An Overview. In: Cho, BK., Tominaga, T. (eds) Moyamoya Disease Update. Springer, Tokyo. https://doi.org/10.1007/978-4-431-99703-0_16
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DOI: https://doi.org/10.1007/978-4-431-99703-0_16
Publisher Name: Springer, Tokyo
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