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Dendritic Cell Vaccines

  • Martin Thurnher
Part of the Allergy Frontiers book series (ALLERGY, volume 6)

Summary

Dendritic cells are the sentinels of the immune system, which instruct the differentiation of helper T cells along various lineages and thus, critically determine the type, intensity, and duration of the immune response. The last decade witnessed the clinical implementation of the dendritic cell vaccination against cancer, which represents a paradigm of translational research and is a contribution to personalized medicine. Dendritic cell-based immunotherapy has been demonstrated to be feasible and well-tolerated and, moreover, to induce immune and clinical responses. The experience gained with dendritic cell therapy of cancer may form the basis for the extension of this therapy to the treatment of allergy and autoimmune disease including transplant rejection.

Keywords

Dendritic Cell Renal Cell Carcinoma Atopic Dermatitis Metastatic Renal Cell Carcinoma Dendritic Cell Maturation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2010

Authors and Affiliations

  1. 1.Department of Urology, Immunotherapy UnitInnsbruck Medical University and KMT Center of Excellence in MedicineInnsbruckAustria

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