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Dendritic Cell Vaccines

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Allergy Frontiers: Future Perspectives

Part of the book series: Allergy Frontiers ((ALLERGY,volume 6))

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Summary

Dendritic cells are the sentinels of the immune system, which instruct the differentiation of helper T cells along various lineages and thus, critically determine the type, intensity, and duration of the immune response. The last decade witnessed the clinical implementation of the dendritic cell vaccination against cancer, which represents a paradigm of translational research and is a contribution to personalized medicine. Dendritic cell-based immunotherapy has been demonstrated to be feasible and well-tolerated and, moreover, to induce immune and clinical responses. The experience gained with dendritic cell therapy of cancer may form the basis for the extension of this therapy to the treatment of allergy and autoimmune disease including transplant rejection.

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Authors and Affiliations

  1. Department of Urology, Immunotherapy Unit, Innsbruck Medical University and KMT Center of Excellence in Medicine, Anichstrasse 35, Innsbruck, 6020, Austria

    Martin Thurnher

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  1. Martin Thurnher
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Correspondence to Martin Thurnher .

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Editors and Affiliations

  1. Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan

    Ruby Pawankar

  2. University of Southampton Southampton General Hospital, Tremona Road, Southampton, UK

    Stephen T. Holgate

  3. Children's Mercy Hospitals and Clinics UMKC School of Medicine, 2401 Gillham Road, Kansas City, MO, 64108, USA

    Lanny J. Rosenwasser

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Thurnher, M. (2010). Dendritic Cell Vaccines. In: Pawankar, R., Holgate, S.T., Rosenwasser, L.J. (eds) Allergy Frontiers: Future Perspectives. Allergy Frontiers, vol 6. Springer, Tokyo. https://doi.org/10.1007/978-4-431-99365-0_17

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  • DOI: https://doi.org/10.1007/978-4-431-99365-0_17

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-99364-3

  • Online ISBN: 978-4-431-99365-0

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