The Natural History of Childhood Asthma

Part of the Allergy Frontiers book series (ALLERGY, volume 5)

The natural history of a disease is defined as a set of interactive processes that involves the underlying defect, the susceptible individual, and the environment. These three variables influence the global process that results in the human response. The result is persistence of the pathophysiology, recovery, or death [1]. Two sequential phases can be identified, the pre-pathogenic period (dependent on the host, the environment and the agent) and the pathogenic period.

Asthma is a complex disease with several rather distinct clinical patterns that make the study and discussion of its natural history a challenging task.


Respiratory Syncytial Virus Fluticasone Propionate Allergy Clin Immunol Childhood Asthma Respir Crit 


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Copyright information

© Springer-Verlag Berlin Heidelberg 2009

Authors and Affiliations

  1. 1.Pediatric DepartmentUniversity of Iowa HospitalIowa CityUSA
  2. 2.Division of Allergy, Clinical Immunology and RheumatologyFederal University of São PauloSão PauloBrazil

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