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The Efficacy of a Bionic Baroreflex System in an Abdominal Aortic Aneurysm Surgery

  • Hideaki Nishimori
  • Takashi Fukutomi
  • Seiichiro Wariishi
  • Masaki Yamamoto
  • Shiro Sasaguri
Conference paper

Purpose: We had proposed a novel therapeutic strategy against central baroreflex failure: implementation of an artificial baroreflex system to automatically regulate sympathetic vasomotor tone, i. e., a bionic baroreflex system (BBS), and tested its efficacy in a model of sudden hypotension during orthopaedic surgery. In present study we utilized a BBS during an abdominal aortic aneurysm surgery to treat hypotension occurred when declamping an aorta.

Method: Ten patients (73–84 years old, 7 males) who underwent abdominal aortic aneurysm repair were enrolled. The BBS consisted of a computer-controlled negative feedback circuit that sensed arterial pressure (AP) and automatically computed the frequency (STM) of a pulse train required to stimulate sympathetic nerves via an epidural catheter placed at the level of the lower thoracic spinal cord.

Keywords

Arterial Pressure Aortic Aneurysm Orthopaedic Surgery Sympathetic Nerve Abdominal Aortic Aneurysm 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer 2009

Authors and Affiliations

  • Hideaki Nishimori
    • 1
  • Takashi Fukutomi
    • 1
  • Seiichiro Wariishi
    • 1
  • Masaki Yamamoto
    • 1
  • Shiro Sasaguri
    • 1
  1. 1.Department of Surgery 2Kochi UniversityKochiJapan

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