Outcome Measures in Asthma Management

  • Michael Schatz
Part of the Allergy Frontiers book series (ALLERGY, volume 4)

Asthma outcomes are important for clinical research and clinical practice. Asthma outcomes represent at least five unique domains: symptoms, quality of life, pulmonary function, inflammatory markers, and exacerbations. Patient-reported outcomes include symptoms, rescue bronchodilator use, functional measures, multidimensional questionnaires (measuring asthma-specific quality of life and control), patient satisfaction, and change in medication requirement. Pulmonary function outcomes include spirometry (including fixed airway obstruction), peak expiratory flow rate, and lung volumes. Markers of airway inflammation include tests of airway hyperresponsiveness (such as methacholine challenge), sputum eosinophilia, and exhaled nitric oxide. Asthma exacerbations include fatal exacerbations and those that require urgent medical care. Asthma outcomes may be assessed using clinical or administrative data. Economic asthma outcomes include total, direct, and indirect costs. This chapter reviews definitions, prevalence, measurement tools, predictors, and interrelationships of the above outcomes.


Forced Vital Capacity Asthma Control Allergy Clin Immunol Respir Crit Asthma Exacerbation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer 2009

Authors and Affiliations

  • Michael Schatz
    • 1
  1. 1.Department of AllergyKaiser Permanente Medical CenterSan DiegoUSA

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