Allergy Diagnosis

  • Pascal Demoly
  • Francesco Gaeta
  • Jean Bousquet
  • Antonino Romano
Part of the Allergy Frontiers book series (ALLERGY, volume 4)

Since the recognition that IgE-mediated allergic diseases are caused by exposure to allergens, the diagnosis of allergies is routinely based upon skin testing and/or specific serum IgE measurements. Skin tests should follow a proper methodology: they utilize negative and positive controls, standardised allergen extracts, and have positivity criteria. Skin tests should always be interpreted in the context of the clinical history. Indeed, false-negative and false-positive skin tests are well known and should be taken into account. Specific IgE measurements are less sensitive but useful in many situations. New diagnostic tools have been developed and are under validation. Their routine use could increase the sensitivity of allergy diagnosis in the future.


Allergic Rhinitis Skin Test Allergy Clin Immunol Basophil Activation Test Recombinant Allergen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer 2009

Authors and Affiliations

  • Pascal Demoly
    • 1
  • Francesco Gaeta
    • 2
  • Jean Bousquet
    • 1
  • Antonino Romano
    • 3
    • 4
  1. 1.Exploration des Allergies — Maladies Respiratoires et INSERM, Hôpital Arnaud de VilleneuveUniversity Hospital of MontpellierMontpellierFrance
  2. 2.Unità di Allergologia, Complesso Integrato ColumbusRomeItaly
  3. 3.Unità di Allergologia, Complesso Integrato ColumbusRomeItaly
  4. 4.IRCCS Oasi Maria S.S.TroinaItaly

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