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Clinical Aspects and Diagnosis of Atopic Eczema

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Allergy Frontiers: Diagnosis and Health Economics

Part of the book series: Allergy Frontiers ((ALLERGY,volume 4))

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Atopic eczema (AE) is characterized by the absence of any specific laboratory test and histopathological finding. In this chapter, the full clinical spectrum of AE is presented. Furthermore, important cutaneous disorders, which have to be delineated are mentioned.

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References

  1. Möhrenschlager M, Darsow U, Schnopp C, Ring J (2006) What is new in atopic eczema? JEADV 20:503–511

    PubMed  Google Scholar 

  2. Rudikoff D, Akhavan A, Cohen SR (2003) Color atlas: eczema. Clin Dermatol 21:101–108

    Article  PubMed  Google Scholar 

  3. Coca AF, Cooke RA (1923) On the classification of the phenomena of hypersensitiveness. J Immunol 8:163–182

    CAS  Google Scholar 

  4. Ring J (2005) Allergy in practice. Springer, Berlin, pp. 86–105

    Google Scholar 

  5. Johansson SG, Hourihane JO, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T, Kowalski ML, Mygind N, Ring J, van Cauwenberge P, van Hage-Hamsten M, Wüthrich B; EAACI (European Academy of Allergology and Cinical Immunology) Nomenclature Task Force (2001) A revised nomenclature for allergy. Allergy 56:813–824

    Article  PubMed  CAS  Google Scholar 

  6. Johansson SG, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, Motala C, Ortega Martell JA, Platts-Mills TA, Ring J, Thien F, van Cauwenberge P, Williams HC (2004) Revised nomenclature for allergy for global use: report of the Nomenclature Review Committee of the World Allergy Organization, October 2003. J Allergy Clin Immunol 113:832–836

    Article  PubMed  CAS  Google Scholar 

  7. Rudikoff D, Lebwohl M (1998) Atopic dermatitis. Lancet 351:1715–1721

    Article  PubMed  CAS  Google Scholar 

  8. Thestrup-Pedersen K (2000) Clinical aspects of atopic dermatitis. Clin Exp Dermatol 25:535–543

    Article  PubMed  CAS  Google Scholar 

  9. Hanifin JM (1991) Atopic dermatitis in infants and children. Pediatr Clin North Am 38:763–789

    PubMed  CAS  Google Scholar 

  10. Abeck D, Burgdorf W, Cremer H (2003) Common skin diseases in children. Steinkopff, Darmstadt, pp. 19–30

    Google Scholar 

  11. Kunz BIF, Ring J (2006) Clinical features and diagnostic criteria of atopic dermatitis. In: Harper J, Oranje A, Prose N (eds.), Textbook of pediatric dermatology (2nd edition). Blackwell, Oxford, pp. 227–244

    Google Scholar 

  12. Dotterud LK, Kvammen B, Lund E, Falk ES (1995) Prevalence and some clinical aspects of atopic dermatitis in the community of Sør-Varanger. Acta Derm Venereol (Stockh) 75:50–53

    CAS  Google Scholar 

  13. Schudel P, Wüthrich B (1985) Klinische Verlaufsbeobachtungen bei Neurodermitis atopica nach dem Kleinkindesalter. Z Hautkr 60:479–486

    PubMed  CAS  Google Scholar 

  14. Cowan MA (1961) Nummular eczema: a review, follow up and analysis of a series of 325 cases. Act Derm Venereol (Stockh) 41:453

    CAS  Google Scholar 

  15. Breit R (1997) Neurodermatitis (Dermatitis atopica) im Kindesalter. Z Hautkr 2(Suppl):72–82

    Google Scholar 

  16. Holden CA, Berth-Jones J (2004) Eczema, lichenification, prurigo and erythroderma. In: Burns T, Breathnach S, Cox N, Griffiths C (eds.), Rook's textbook of dermatology (vol. 1) (7th edition). Blackwell, Oxford, pp. 17.1–17.55

    Google Scholar 

  17. Neering H, van Dijk E (1978) Juvenile plantar dermatosis. Acta Derm Venereol (Stockh) 58:531–534

    CAS  Google Scholar 

  18. Kint A, van Hecke E, Leys G (1982) Dermatitis plantaris sicca. Dermatologica 165:500–509

    PubMed  CAS  Google Scholar 

  19. Jones SK, English JS, Forsyth A, Mackie RM (1987) Juvenile plantar dermatosis — an 8-year follow-up of 102 patients. Clin Exp Dermatol 12:5–7

    Article  PubMed  CAS  Google Scholar 

  20. Svensson A, Moiler H (1986) Eyelid dermatitis: the role of atopy and contact allergy. Contact Dermatitis 15:178–182

    Article  PubMed  CAS  Google Scholar 

  21. Rudzki E, Samochocki Z, Rebandel P, Saciuk E, Galecki W, Raczka A, Szmurlo A (1994) Frequency and significance of the major and minor features of Hanifin and Rajka among patients with atopic dermatitis. Dermatology 189:41–46

    PubMed  CAS  Google Scholar 

  22. Mevorah B, Frenk E, Wietlisbach V, Carrel CF (1988) Minor clinical features of atopic dermatitis. Dermatologica 177:360–364

    PubMed  CAS  Google Scholar 

  23. Diepgen TL, Fartasch M (1992) Recent epidemiological and genetic studies in atopic dermatitis. Acta Derm Venereol (Stockh) 176(suppl):13–18

    CAS  Google Scholar 

  24. Przybilla B, Ring J, Enders F, Winkelmann H (1991) Stigmata of atopic constitution in patients with atopic eczema or atopic respiratory disease. Acta Derm Venereol (Stockh) 71:407–410

    CAS  Google Scholar 

  25. Svensson A (1989) Xerosis and a history of dry skin. In: Svensson A (ed.), Diagnosis of atopic skin disease based on clinical criteria. Lund University Press, Kristianstad, pp. 41–43

    Google Scholar 

  26. Linde YW (1992) Dry skin in atopic dermatitis. Acta Derm Venereol Suppl (Stockh) 177:9–13

    CAS  Google Scholar 

  27. Werner Y, Lindberg M (1982) The water-binding capacity of stratum corneum in non-ecze-matous skin of atopic eczema. Acta Derm Venereol (Stockh) 62:334–337

    CAS  Google Scholar 

  28. Eberlein-König B, Schäfer T, Huss-Marp J, Darsow U, Möhrenschlager M, Herbert O, Abeck D, Krämer U, Behrendt H, Ring J (2000) Skin surface pH, stratum corneum hydration, trans-epidermal water loss and skin roughness related to atopic eczema and skin dryness in a population of primary school children. Acta Derm Venereol (Stockh) 80:188–191

    Article  Google Scholar 

  29. Przybilla B, Bauer C (2005) Stigmata of the atopic constitution. In: Ring J, Przybilla B, Ruzicka T (eds.), Handbook of atopic eczema (2nd edition). Springer, Berlin, pp. 61–73

    Google Scholar 

  30. Morgan DB (1948) A suggestive sign of allergy. Arch Dermatol Syphol 57:1050–1053

    CAS  Google Scholar 

  31. Williams HC, Pembroke AC (1996) Infraorbital crease, ethnic group, and atopic dermatitis. Arch Dermatol 132:51–54

    Article  PubMed  CAS  Google Scholar 

  32. Whitfield A (1938) On the white reaction in dermatology. Br J Dermatol 50:71–76

    Article  Google Scholar 

  33. Aizawa H, Tagami H (1989) Inability to produce white dermographism in the early stage of infantile eczema. Pediatr Dermatol 6:6–9

    Article  PubMed  CAS  Google Scholar 

  34. Judge MR, McLean WHI, Munro CS (2004) Disorders of keratinization. In: Burns T, Breathnach S, Cox N, Griffiths C (eds.), Rook's textbook of dermatology (vol. 2) (7th edition). Blackwell, Oxford, pp. 34.1–34.111

    Google Scholar 

  35. Marks MB (1977) Recognizing the allergic person. Am Fam Physician 16:72–79

    PubMed  CAS  Google Scholar 

  36. Hurwitz S (2006) Clinical pediatric dermatology (3rd edition). Elsevier/W.B. Saunders, Philadelphia, pp. 49–64

    Google Scholar 

  37. Levy Y, Segal N, Ben-Amitai D, Danon YL (2004) Eyelash length in children and adolescents with allergic disease. Pediatr Dermatol 21:534–537

    Article  PubMed  CAS  Google Scholar 

  38. Möhrenschlager M, Weidinger S, Huss-Marp J, Krämer U, Behrendt H, Ring J (2005) Do gender-specific differences in eyelash length in 5- to 6-year-old preschool children with and without atopic eczema exist? Results from the MIRIAM study conducted in Augsburg, Germany. Pediatr Dermatol 22:576–577

    Article  PubMed  Google Scholar 

  39. Hanifin JM, Rajka G (1980) Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh) 92(Suppl):44–47

    Google Scholar 

  40. Diepgen TL, Sauerbrei W, Fartasch M (1996) Development and validation of diagnostic scores for atopic dermatitis incorporating criteria of data quality and practical usefulness. J Clin Epidemiol 49:1031–1038

    Article  PubMed  CAS  Google Scholar 

  41. Williams HC, Burney PG, Hay RJ, Archer CB, Shipley MJ, Hunter JJ, Bingham EA, Finlay AY, Pembroke AC, Graham-Brown RA (1994) The U.K. working party's diagnostic criteria for atopic dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis. Br J Dermatol 131:383–396

    Article  PubMed  CAS  Google Scholar 

  42. Bos JD, van Leent EJ, Sillevis Smitt JH (1998) The millennium criteria for the diagnosis of atopic dermatitis. Exp Dermatol 7:132–138

    Article  PubMed  CAS  Google Scholar 

  43. Schultz-Larsen F, Hanifin JM (1992) Secular change in the occurrence of atopic dermatitis. Acta Derm Venereol (Stockh) 176(suppl):7–12

    CAS  Google Scholar 

  44. Svensson A, Edman B, Möller H (1985) A diagnostic tool for atopic dermatitis based on clinical criteria. Acta Derm Venereol (Stockh) 114(suppl):33–40

    CAS  Google Scholar 

  45. Visscher MO, Hanifin JM, Bowman WJ (1989) Atopic dermatitis and atopy in non-clinical populations. Acta Derm Venereol (Stockh) 144(suppl):34–40

    CAS  Google Scholar 

  46. Williams HC, Burney PGJ, Strachan D, Hay RJ (1994) The UK working party's diagnostic criteria for atopic dermatitis. II: observer variation of clinical diagnosis and signs of atopic dermatitis. Br J Dermatol 131:397–405

    Article  PubMed  CAS  Google Scholar 

  47. Möhrenschlager M, Schäfer T, Williams HC, von der Werth J, Krämer U, Behrendt H, Ring J (1998) Übersetzung und Validierung der britischen Diagnosekriterien des atopischen Ekzems bei 8- und 9- jährigen Schulkindern in Augsburg. Allergo J 7:373–377

    Google Scholar 

  48. European Task Force on Atopic Dermatitis (1993) Severity scoring of atopic dermatitis: the SCORAD index. Dermatology 186:23–31

    Article  Google Scholar 

  49. Yates VM, Kerr REI, MacKie RM (1983) Early diagnosis of infantile seborrhoeic dermatitis and atopic dermatitis-clinical features. Br J Dermatol 108:633–638

    Article  PubMed  CAS  Google Scholar 

  50. Yates VM, Kerr REI, MacKie RM (1983) Early diagnosis of infantile seborrhoeic dermatitis and atopic dermatitis-total and specific IgE levels. Br J Dermatol 108:639–645

    Article  PubMed  CAS  Google Scholar 

  51. Prendiville JS (2006) Scabies and lice. In: Harper J, Oranje A, Prose N (eds.), Textbook of pediatric dermatology (2nd edition). Blackwell, Oxford, pp. 659–673

    Google Scholar 

  52. Saurat JH (1985) Eczema in primary immune deficiencies. Clues to the pathogenesis of atopic dermatitis with special reference of the Wiskott-Aldrich syndrome. Acta Derm Venereol (Stockh) 114:125–128

    CAS  Google Scholar 

  53. Plebani A, Ugazio AG, Monafo V (1989) Selective IgA deficiency: an update. Curr Probl Dermatol 18:66–78

    PubMed  CAS  Google Scholar 

  54. Buckley RH, Fiscus SA (1975) Serum IgD and IgE concentrations in immunodeficiency diseases. J Clin Invest 55:157–165

    Article  PubMed  CAS  Google Scholar 

  55. Ring J, Landthaler M (1989) Hyper IgE syndromes. Curr Probl Dermatol 18:79–88

    PubMed  CAS  Google Scholar 

  56. Amman AJ (1987) Cutaneous manifestations of immunodeficiency disorders. In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF (eds.), Dermatology in general medicine (3rd edition). McGraw-Hill, New York, pp. 2507–2522

    Google Scholar 

  57. Möhrenschlager M, Schäfer T, Huss-Marp J, Eberlein-König B, Weidinger S, Ring J, Behrendt H, Krämer U (2006) The course of eczema in children aged 5–7 years and its relation to atopy: differences between boys and girls. Br J Dermatol 154:505–513

    Article  PubMed  Google Scholar 

  58. Nelson HS (1995) Clinical application of immediate skin testing. In: Spector SL (ed.), Provocation testing in clinical practice. Marcel Dekker, New York, pp. 703–727

    Google Scholar 

  59. Wüthrich B, Fuchs W (1979) Serum IgE levels in atopic diseases in childhood. Helv Paediatr Acta 34:537–544

    PubMed  Google Scholar 

  60. Ahlstedt S (2002) Understanding the usefulness of specific IgE tests in allergy. Clin Exp Allergy 32:11–16

    Article  PubMed  CAS  Google Scholar 

  61. Yman L (2001) Standardization of in vitro methods. Allergy 56(suppl 67):70–74

    Article  PubMed  Google Scholar 

  62. Dolen WK (1999) Skin testing and immunoassays for allergen-specific IgE: a workshop report. Ann Allergy Asthma Immunol 82:407–412

    Article  Google Scholar 

  63. Sanz ML, Prieto I, Garcia BE, Oehling A (1996) Diagnostic reliability considerations of specific IgE determination. J Investig Allergol Clin Immunol 6:152–161

    PubMed  CAS  Google Scholar 

  64. Mitchell EB, Crow J, Chapman MD, Jouhal SS, Pope FM, Platts-Mills TAE (1982) Basophils in allergen-induced patch test sites in atopic dermatitis. Lancet 1:127–130

    Article  PubMed  CAS  Google Scholar 

  65. Ring J, Darsow U, Gfesser M, Vieluf D (1997) The ‘atopy patch test’ in evaluating the role of aeroallergens in atopic eczema. Int Arch Allergy Immunol 113:379–383

    Article  PubMed  CAS  Google Scholar 

  66. Gondo A, Saeki N, Tokuda Y (1986) Challenge reactions in atopic dermatitis after percutaneous entry of mite antigen. Br J Dermatol 115:485–493

    Article  PubMed  CAS  Google Scholar 

  67. Bruijnzeel PL, Kuijper PH, Kapp A, Warringa RA, Betz S, Bruijnzeel-Koomen CA (1993) The involvement of eosinophils in the patch test reaction to aeroallergens in atopic dermatitis: its relevance for the pathogenesis of atopic dermatitis. Clin Exp Allergy 23:97–109

    Article  PubMed  CAS  Google Scholar 

  68. Adinoff AD, Tellez P, Clark RA (1988) Atopic dermatitis and aeroallergen contact sensitivity. J Allergy Clin Immunol 135:182–186

    Google Scholar 

  69. Clark RA, Adinoff AB (1989) Aeroallergen contact can exacerbate atopic dermatitis: patch tests as a diagnostic tool. J Am Acad Dermatol 21:863–869

    Article  PubMed  CAS  Google Scholar 

  70. Imayama S, Hashizume T, Miyahara H, Tanahashi T, Takeishi M, Kubota Y, Koga T, Hori Y, Fukuda H (1992) Combination of patch test and IgE for dust mite antigens differentiates 130 patients with atopic dermatitis into four groups. J Am Acad Dermatol 27:531–538

    Article  PubMed  CAS  Google Scholar 

  71. Darsow U, Vieluf U, Ring J (1996) The atopy patch test: an increased rate of reactivity in patients who have an air-exposed pattern of atopic eczema. Br J Dermatol 135:182–186

    Article  PubMed  CAS  Google Scholar 

  72. Darsow U, Vieluf U, Ring J (1999) Evaluating the relevance of aeroallergen sensitization in atopic eczema with the atopy patch test: a randomized, double-blind multicenter study. J Am Acad Dermatol 40:187–193

    Article  PubMed  CAS  Google Scholar 

  73. Darsow U, Vieluf D, Ring J (1995) Atopy patch test with different vehicles and allergen concentrations: an approach to standardization. J Allergy Clin Immunol 95:677–684

    Article  PubMed  CAS  Google Scholar 

  74. Darsow U, Ring J (2000) Airborne and dietary allergens in atopic eczema: a comprehensive review of diagnostic tests. Clin Exp Dermatol 25:544–551

    Article  PubMed  CAS  Google Scholar 

  75. Bruijnzeel PL, Kuijper PH, Kapp A, Warringa RA, Betz S, Bruijnzeel-Koomen CA (1993) The involvement of eosinophils in the patch test reaction to aeroallergens in atopic dermatitis: its relevance for the pathogenesis of atopic dermatitis. Clin Exp Allergy 23:97–109

    Article  PubMed  CAS  Google Scholar 

  76. Darsow U, Laifaoui J, Kerschenlohr K, Wollenberg A, Przybilla B, Wüthrich B, Borelli S, Giusti F, Seidenari S, Drzimalla K, Simon D, Disch R, Borelli S, Devillers AC, Oranje AP, de Raeve L, Hachem JP, Dangoisse C, Blondeel A, Song M, Breuer K, Wulf A, Werfel T, Roul S, Taieb A, Bolhaar S, Bruijnzeel-Koomen C, Brönnimann M, Braathen LR, Didierlaurent A, André C, Ring J (2004) The prevalence of positive reactions in the atopy patch test with aer-oallergens and food allergens in subjects with atopic eczema: a European multicenter study. Allergy 59:1318–1325

    Article  PubMed  CAS  Google Scholar 

  77. Langeveld-Wildschut EG, van Marion AM, Thepen T, Mudde GC, Bruijnzeel PL, Bruijnzeel-Koomen CA (1995) Evaluation of variables influencing the outcome of the atopy patch test. J Allergy Clin Immunol 96:66–73

    Article  PubMed  CAS  Google Scholar 

  78. Langeveld-Wildschut EG, Riedl H, Thepen T, Bihari IC, Bruijnzeel PL, Bruijnzeel-Koomen CA (2000) Modulation of the atopy patch test reaction by topical corticosteroids and tar. J Allergy Clin Immunol 106:737–743

    Article  PubMed  CAS  Google Scholar 

  79. Høst A, Andrae S, Charkin S, Diaz-Vázquez C, Dreborg S, Eigenmann PA, Friedrichs F, Grinsted P, Lack G, Meylan G, Miglioranzi P, Muraro A, Nieto A, Niggemann B, Pascual C, Pouech MG, Rancé F, Rietschel E, Wickman M (2003) Allergy testing in children: why, who, when and how? Allergy 58:559–569

    Article  PubMed  Google Scholar 

  80. Darsow U, Ring J (2002) Allergy diagnosis in atopic eczema with the atopy patch test. In: Bieber T, Leung DY (eds.), Atopic dermatitis. Marcel Dekker, New York, pp. 86–105

    Google Scholar 

  81. Schultz-Larsen F (1993) Atopic dermatitis: a genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 28:719–723

    Article  PubMed  CAS  Google Scholar 

  82. Cookson WO, Ubhi B, Lawrence R, Abecasis GR, Walley AJ, Cox HE, Coleman R, Leaves NI, Trembath RC, Mofatt MF, Harper IJ (2001) Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nat Genet 27:372–373

    Article  PubMed  CAS  Google Scholar 

  83. Cookson WO, Moffatt MF (2002) The genetics of atopic dermatitis. Curr Opin Allergy Immunol 2:383–387

    Article  Google Scholar 

  84. Leung DYM, Jain N, Leo HL (2003) New concepts in the pathogenesis of atopic dermatitis. Curr Opin Immunol 15:634–638

    Article  PubMed  CAS  Google Scholar 

  85. Lee YA, Wahn U, Kehrt R, Tarani L, Businco L, Gustafsson D, Andersson F, Oranje AP, Wolkertstorfer A, von Berg A, Hoffmann U, Küster W, Wienker T, Rüschendorf F, Reis A (2001) A major susceptibility locus for atopic dermatitis maps to chromosome 3q21. Nat Genet 26:470–473

    Article  CAS  Google Scholar 

  86. Tamura K, Suzuki M, Arakawa H, Tokuyama K, Morikawa A (2003) Linkage and association studies of STAT6 gene polymorphisms and allergic diseases. Int Arch Allergy Immunol 131:33–38

    Article  PubMed  CAS  Google Scholar 

  87. Novak N, Kruse S, Kraft S, Geiger E, Klüken H, Fimmers R, Deichmann KA, Bieber T (2002) Dichotomic nature of atopic dermatitis reflected by combined analysis of monocyte immunophenotyping and single nucleotide polymorphisms of the interleukin-4/interleukin-13 receptor gene: the dichotomy of extrinsic and intrinsic atopic dermatitis. J Invest Dermatol 119:870–875

    Article  PubMed  CAS  Google Scholar 

  88. Arkwright PD, Chase JM, Babbage S, Pravica V, David TJ, Hutchinson IV (2001) Atopic dermatitis is associated with a low-producer transforming growth factor beta(1) cytokine genotype. J Allergy Clin Immunol 108:281–284

    Article  PubMed  CAS  Google Scholar 

  89. Yagi R, Nagai H, Iigo Y, Akimoto T, Arai T, Kubo M (2002) Development of atopic dermatitis-skin lesions in STAT6-deficient NC/Nga mice. J Immunol 168:2020–2027

    PubMed  CAS  Google Scholar 

  90. Weidinger S, O'sullivan M, Illig T, Baurecht H, Depner M, Rodriguez E, Ruether A, Klopp N, Vogelberg C, Weiland SK, McLean WH, von Mutius E, Irvine AD, Kabesch M (2008) Filaggrin mutations, atopic eczema, hay fever, and asthma in children. J Allergy Clin Immunol 121:1203–1209

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Division of Environmental Dermatology and Allergology GSF/TUM, Department of Dermatology and Allergy Biederstein, Technical University of Munich, Biedersteiner Street 29, Munich, D-80802, Germany

    Matthias Möhrenschlager, Stephan Weidinger & Johannes Ring

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  1. Matthias Möhrenschlager
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  2. Stephan Weidinger
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  3. Johannes Ring
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  1. Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan

    Ruby Pawankar

  2. Southampton General Hospital, University of Southampton, Tremona Road, Southampton, UK

    Stephen T. Holgate

  3. UMKC School of Medicine, Children's Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO, 64108, USA

    Lanny J. Rosenwasser

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Möhrenschlager, M., Weidinger, S., Ring, J. (2009). Clinical Aspects and Diagnosis of Atopic Eczema. In: Pawankar, R., Holgate, S.T., Rosenwasser, L.J. (eds) Allergy Frontiers: Diagnosis and Health Economics. Allergy Frontiers, vol 4. Springer, Tokyo. https://doi.org/10.1007/978-4-431-98349-1_17

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