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Human Population Genetics Meets Medaka

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Medaka

Abstract

A significant feature of Medaka (Oryzias latipes) is its well-known genetic, morphological and physiological diversity. Population studies of medaka have shown that it is a promising candidate for a “vertebrate” model system of population genetics. The study of genome diversity in humans is one of the key postgenome sequencing projects, accomplished by analyzing genetic polymorphisms in human populations, although in most cases little is known as to what functional differences are induced by polymorphisms and what effect they have on human adaptation. We expect that Medaka populations can be a useful model to examine the relationship between allelic functional differences and habitat environment as an analogy of human populations. Herein we review the potential usefulness of Medaka in the study of human population genetics.

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Author notes

  1. Hiroshi Mitani

    Present address: Department of Anatomy, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0374, Japan

Authors and Affiliations

  1. Department of Integrated Biosciences, Graduate School of Frontier Science, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8562, Japan

    Hiroki Oota

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  1. Hiroki Oota
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Correspondence to Hiroki Oota or Hiroshi Mitani .

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Editors and Affiliations

  1. Laboratory of Bioresources, National Institute for Basic Biology, 38 Nishigonaka, Myodaiji, Okazaki, Aichi, 444-8585, Japan

    Kiyoshi Naruse Ph.D. (Associate Professor) (Associate Professor)

  2. Laboratory of Molecular Genetics for Reproduction, National Institute for Basic Biology, 5-1 Higashiyama, Myodaiji, Okazaki, Aichi, 444-8787, Japan

    Minoru Tanaka Ph.D. (Associate Professor) (Associate Professor)

  3. Department of Biological Sciences Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan

    Hiroyuki Takeda Ph.D. (Professor) (Professor)

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Oota, H., Mitani, H. (2010). Human Population Genetics Meets Medaka. In: Naruse, K., Tanaka, M., Takeda, H. (eds) Medaka. Springer, Tokyo. https://doi.org/10.1007/978-4-431-92691-7_22

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