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Mechanical Stress and Bone

  • Masaki Noda
  • Tadayoshi Hayata
  • Tetsuya Nakamoto
  • Takuya Notomi
  • Yoichi Ezura

Abstract

Bone has been known to adapt to mechanical stress (Amin 2010; Beier and Loeser 2010; Currey 2010; Temiyasathit and Jacobs 2010). The presence of mechanical stress increases bone mass and the absence of mechanical stress reduces bone mass. Bending of weight-bearing long bone increases pressure on the concave side and decreases it on the convex side. Under such circumstances, bone is accumulated on the concave side and is reduced on the convex side. This can be seen after angular deformity due to malunion of fractures in children where minor angular deformity could be corrected during the growth of the children.

Keywords

Bone Resorption Bone Marrow Cell Bone Formation Rate Mineral Apposition Rate Osteoclast Surface 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2011

Authors and Affiliations

  • Masaki Noda
    • 1
  • Tadayoshi Hayata
    • 1
  • Tetsuya Nakamoto
    • 1
  • Takuya Notomi
    • 1
  • Yoichi Ezura
    • 1
  1. 1.Department of Molecular Pharmacology, Division of Advanced Molecular Medicine, Medical Research InstituteTokyo Medical and Dental UniversityBunkyo-kuJapan

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