Mechanisms of Nocturnal Asthma

  • Krzysztof Kowal
  • Lawrence Du Buske
Part of the Allergy Frontiers book series (ALLERGY, volume 3)


Nocturnal deterioration of lung function frequently occurs in asthma patients. It results in sleep depravation and impaired quality of life but is also associated with increased morbidity and mortality. Several mechanisms such as endogenous circadian rhythm disturbances, concomitant disorders, behavioral and environmental factors have been implicated in the pathophysiology of nocturnal asthma symptoms. Appropriately used, currently available asthma medications, including long acting beta agonists and inhaled corticosteroids are effective in therapy of nocturnal asthma symptoms in the majority of patients.


Obstructive Sleep Apnea Allergy Clin Immunol Respir Crit Circadian Variation Tiotropium Bromide 


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Copyright information

© Springer 2009

Authors and Affiliations

  • Krzysztof Kowal
    • 1
  • Lawrence Du Buske
    • 2
  1. 1.Medical University of BialystokBialystokPoland
  2. 2.Brigham and Women's Hospital Harvard Medical SchoolBostonUSA

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