Metabolic Information Highway: Interorgan Metabolic Communication Via the Autonomic Nervous System

  • Hideki Katagiri
Conference paper

Our research goals are the development of therapeutic strategies for diabetes mellitus.

The incidence of obesity is rising at an alarming rate in much of the world [1]. Obesity, especially visceral obesity, is prone to be associated with hypertension, glucose intolerance, and dyslipidemia, collectively termed the metabolic syndrome. Independently of hypercholesterolemia, especially increased levels of oxidized low density lipoproteins [2], the metabolic syndrome increases the risk for atherosclerosis and cardiovascular morbidities [1]. To overcome obesity-related diabetes and the metabolic syndrome, it seems to be necessary to treat obesity itself. Therefore, we have attempted to unravel and manipulate the regulatory systems governing body weight as well as energy metabolism.


Metabolic Syndrome Visceral Adipose Tissue Neuronal Signal Metabolic Communication Remote Tissue 
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Copyright information

© Springer 2009

Authors and Affiliations

  • Hideki Katagiri
    • 1
  1. 1.Division of Advanced Therapeutics for Metabolic Diseases, Center for Translational and Advanced Animal ResearchTohoku University Graduate School of MedicineAoba-kuJapan

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