Structural Analysis of Phospho-Glycosphingolipids in Lower Animals
Phosphoric acid is a key compositional element of ATP which provides biochemical energy as well as contributes to the nucleic acid backbone in all organisms. It is also an indispensable element in the phospholipid component of biomembranes. Phosphoglycosphingolipid (PGSL) contains phosphoric acid as a charged group (Fig. 1). Numerous PGSLs have been reported in invertebrates, and it is possible that they are the functional counterpart in invertebrates to the acidic glycosphingolipid, ganglioside in vertebrates. It is thus important to gain a better understanding of PGSL compounds and their structures, and their distribution in the animal kingdom (Hori and Sugita 1993; Itonori and Sugita 2005; Itonori and Sugita 2007).
KeywordsFunctional Counterpart Choline Phosphate Biochemical Energy Freshwater Leech Florisil Column Chromatography
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