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Structural Analyses of Glycoconjugates by NMR

  • Koichi Kato
  • Yoshiki Yamaguchi

Abstract

NMR spectroscopy has been one of the most powerful methods to obtain structural information of oligosaccharides. Vliegenthart and co-workers have greatly achieved systematic studies on 1H chemical shifts of oligosaccharides and thereby described numerous structures by using a “structural reporter group” (Vliegenthart 1980). Recent advances in NMR and stable isotope labeling techniques have made possible not only determination of covalent structure of oligosaccharides but also analyses of conformations and dynamics of glycoconjugates, which are usually inaccessible by X-ray crystallography.

Keywords

Residual Dipolar Coupling Stable Isotope Label Spin Coupling Constant Alignment Tensor GlcNAc Residue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2008

Authors and Affiliations

  • Koichi Kato
    • 1
  • Yoshiki Yamaguchi
    • 1
  1. 1.Graduate School of Pharmaceutical SciencesNagoya City UniversityNagoyaJapan

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