Fucosyltransferase (α1,2/ α1,3/ α1,4-fucosyltransferases)
Many studies using monoclonal antibodies have demonstrated that fucosylated carbohydrate chains are involved in various physiological functions including development, neuronal activity, and cancerous transformation. The genes encoding fucosyltransferases which synthesize fucosylated carbohydrate antigens have been cloned, and their function has been gradually elucidated by analyses of their substrate specificities and biological functions (Taniguchi et al. 2002).
KeywordsCarbohydrate Chain Blood Group Antigen System Blood Group Cancerous Transformation Lewis Blood Group
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