Bombay, Lewis and Ii Blood Group Antigens on Human Erythrocytes

  • Hisashi Narimatsu


Representatives of blood groups determined by carbohydrate antigens are Lewis, ABO, P, and Ii blood group systems. The synthetic pathway of carbohydrate antigens of ABO and Lewis blood groups is shown in Fig. 1. The type of a carbohydrate blood group antigen is determined by the genetic difference of the carbohydrate synthesized by glycosyltransferases in individuals, and the difference occurs by loss of activity or change in the substrate specificity of glycosyltransferases, mainly due to the point mutation in their gene.


Blood Group Carbohydrate Antigen Digestive Organ Congenital Cataract Blood Group Antigen 
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© Springer 2008

Authors and Affiliations

  • Hisashi Narimatsu
    • 1
  1. 1.Research Center for Medical GlycosciencesNational Institute of Advanced Industrial Science and Technology (AIST)Tsukuba, IbarakiJapan

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