A Novel Lectin-Affinity Database for Structural Glycomics
Lectins, non-enzymatic glycan-binding proteins, are ubiquitous in nature and act as recognition molecules in many biological processes including cell-cell and cell-molecule interactions, innate immunity, morphogenesis and fertilization. Over the past 120 years numerous lectins have been isolated from plants, microorganisms, fungi, animals and viruses, resulting in a wealth of data. Lectins are also used as invaluable tools for the detection, isolation and characterization of various glycoproteins, or for histopathological examination of cells and tissues and for clinical diagnosis of carcinoma and leukemia.
KeywordsGlycan Structure Invaluable Tool Mass Spectral Library Simultaneous Manner Lectin Microarray
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