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A Database System for Glycogenes (GGDB)

  • Akira Togayachi
  • Kwon-Yeon Dae
  • Toshihide Shikanai
  • Hisashi Narimatsu

Abstract

Glycogenes include genes of glycosyltransferase, sugar-nucleotide synthase, sugar-nucleotide transporter, sulfotransferase, etc. A total of 184 glycogenes are known to exist, and the authors collected the data of human glycogenes including the newly found ones in the “Construction of Glycogene Library” project (April 2001–March 2004) (Narimatsu 2004). There has been no database which comprehensively stores the information on human glycogenes. At present, over 184 genes of human glycosyltransferases and sulfotransferases are identified, cloned and expressed in various expression systems to analyze the activity for carbohydrate synthesis and its biological function. Therefore, in order to enable one-stop search of information necessary for the analysis of glycogenes, we constructed GlycoGene Database (GGDB) (Kwon 2004) which comprehensively includes all information of glycogenes obtained to date, and equips functions for analysis of homology and other purposes.

Keywords

Gene Symbol Carbohydrate Chain Hydrophobic Amino Acid Residue CAZy Database Carbohydrate Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Kwon Y-D GGDB (2004) A database system for glycogenes. The second symposium of Japanese consortium for glycobiology and glycotechnology, pp 42–43Google Scholar
  2. Narimatsu H (2004) Construction of a human glycogene library and comprehensive functional analysis. Glycoconj J 21:17–24PubMedCrossRefGoogle Scholar
  3. Website of JCGGDB (also link to GGDB from here) http://jcggdb.jpGoogle Scholar
  4. Website of Research Center for Glycoscience, AIST (also link to GGDB from here), http://unit.aist.go.jp/rcmg/ci/index.htmlGoogle Scholar

Copyright information

© Springer 2008

Authors and Affiliations

  • Akira Togayachi
    • 1
  • Kwon-Yeon Dae
    • 1
  • Toshihide Shikanai
    • 1
  • Hisashi Narimatsu
    • 1
  1. 1.Research Center for Medical Glycoscience (RCMG)National Institute of Advanced Industrial Science and Technology (AIST)Tsukuba, IbarakiJapan

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