Fatigue: Epidemiology and Social/Industrial Aspects
There is no doubt that the symptoms of fatigue are costly for both society and for the individual. Fatigue is found in a spectrum of diseases and illnesses caused by pathology in biological systems, but also by environmental factors which directly or indirectly influence biological systems in the human body. Although it has been known for a long time that more women than men suffer from this group of illnesses, little research has focused on the influence of gender, e.g., the circumstances which women and men live under, on the outcome of fatigue-related health problems. The complex interaction between different regulatory systems connecting body, soul, and mind is clearer today as molecular techniques are being developed. Data on a genetic linkage to chronic fatigue have also been established.
KeywordsSick Leave Chronic Fatigue Syndrome Latent Class Analysis Negative Life Event Chronic Fatigue Syndrome Patient
Unable to display preview. Download preview PDF.
- 4.Jones JF, Kohl KS, Ahmadipour N, Bleijenberg G, Buchwald D, Evengard B, Jason LA, Klimas NG, Lloyd A, McCleary K, Oleske JM, White PD; The Brighton Collaboration Fatigue Working Group (2007) Fatigue: Case definition and guidelines for collection, analysis, and presentation of immunization safety data. Vaccine. March 12: Epub ahead of printGoogle Scholar
- 11.Kerr JR, Christian P, Hodgetts A, et al. (2006) Current research priorities in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): disease mechanisms, a diagnostic test and specific treatments. J Clin Pathol Aug 25, Epub ahead of printGoogle Scholar
- 14.Beard GM (1869) Neurasthenia, or nervous exhaustion. Boston Med Surg J 80:217–221Google Scholar
- 40.Kato K, Sullivan PF, Evengård B, Pedersen NL. Premorbid predictors of chronic fatigue. Arch Gen Psychiatr, in pressGoogle Scholar
- 41.Gräns H, Nilsson M, Dahlman-Wright K, Evengard B (2006) Levels of estrogen receptor alpha, beta and betacx mRNA in Swedish patients with chronic fatigue syndrome. J Clin Pathol May 26, EpubGoogle Scholar
- 42.Rajeevan MS, Smith AK, Dimulescu I, Unger ER, Vernon SD, Heim C, Reeves WC (2006) Glucocorticoid receptor polymorphisms and haplotypes associated with chronic fatigue syndrome. Genes Brain Behav Jun 1, EpubGoogle Scholar
- 43.Gupta S, Aslakson E, Gorbaxani BH, Vernon SD (2002) Inclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability. Theor Biol Med Model Feb 14;4:8Google Scholar