Neural Basis of Saccadic Decision Making in the Human Cortex

  • Samson Freyermuth
  • Jean-Philippe Lachaux
  • Philippe Kahane
  • Alain Berthoz


We summarize a few of the brain imaging studies on cortical control of ocular saccades (including the main eye fields: PEF, FEF, SEF, CEF, pre-SEF, PFEF) and describes recent new findings obtained with intracranial recordings of brain activity in epileptic patients (Stereotaxic EEG). We shall particularly focus on the problem of decision making in saccadic control by describing experiments during which subjects had to decide to make an horizontal saccade to a particular direction in space. Oculomotor execution and decision can be studied only by integrating dynamic component. The SEEG signals clearly reveal the multidimensionality of the ensemble neuronal responses, which consist of event-related potentials (ERPs), induced synchronizations and desynchronizations in distinct frequency bands. Our short study show a specific activation in the high frequencies (very high gamma band: 110–140 Hz) of the PFEF in an oculomotor task when the decision is needed.


Prefrontal Cortex Transcranial Magnetic Stimulation Antisaccade Task Saccade Generation Saccade Goal 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer 2007

Authors and Affiliations

  • Samson Freyermuth
    • 1
  • Jean-Philippe Lachaux
    • 2
  • Philippe Kahane
    • 3
  • Alain Berthoz
    • 1
  1. 1.Laboratoire de Physiologie de la Perception et de l’Action, CNRSCollège de FranceParisFrance
  2. 2.Inserm U280. Mental processes and brain activationCentre Hospitalier Le VinatierBronFrance
  3. 3.Department of Neurology and JE2413 Research UnitGrenoble HospitalGrenobleFrance

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