A positive surgical margin associated with an extraprostatic extension of prostate carcinoma is a significant risk for disease progression. What, then, is the risk of a positive margin created by an inadvertent surgical incision into cancerous prostate parenchyma?
In our daily practice there are several situations in which positive surgical margins are questioned. The first is a positive margin that has resulted because a tumor extending outside the prostate reaching the inked periprostatic tissue margin. A second situation is a positive margin created by an accidental surgical incision into cancerous prostate parenchyma. The third is an equivocal “positive” margin created when the surface of the pathology specimen had a disrupted appearance and the tumor reached the inked edge of the prostate. The third incidence may occur in association with either of the first two situations.
KeywordsRadical Prostatectomy Positive Margin Positive Surgical Margin Distal Margin Apical Margin
Unable to display preview. Download preview PDF.
- 1.Sakr WA, Wheeler TM, Blute M, Bodo M, Callee-Rodrique R, Henson DE, Mostofi FK, Seiffert J, Wojno K, Zincke H (1996) International consultation on prostatic intraepithelial neoplasia and pathologic staging of prostate cancer; Work Group 2: staging and reporting of prostate cancer-sampling of radical prostatectomy specimen. Cancer 78:366–368.PubMedCrossRefGoogle Scholar
- 7.Epstein JI, Pizov G, Walsh PC (1993) Correlation of pathologic findings with progression after radical retropubic prostatectomy. Cancer 71:3583–3593.Google Scholar