Abstract
In our daily practice there are several situations in which positive surgical margins are questioned. The first is a positive margin that has resulted because a tumor extending outside the prostate reaching the inked periprostatic tissue margin. A second situation is a positive margin created by an accidental surgical incision into cancerous prostate parenchyma. The third is an equivocal “positive” margin created when the surface of the pathology specimen had a disrupted appearance and the tumor reached the inked edge of the prostate. The third incidence may occur in association with either of the first two situations.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Sakr WA, Wheeler TM, Blute M, Bodo M, Callee-Rodrique R, Henson DE, Mostofi FK, Seiffert J, Wojno K, Zincke H (1996) International consultation on prostatic intraepithelial neoplasia and pathologic staging of prostate cancer; Work Group 2: staging and reporting of prostate cancer-sampling of radical prostatectomy specimen. Cancer 78:366–368.
Bostwick DG (1997) Staging prostate cancer—1997: current methods and limitation. Eur Urol 32(suppl): 2–14.
Watson RB, Civantos F, Soloway MS (1996) Positive margins with radical prostatectomy: detailed pathological analysis and prognosis. Urology 48:80–90.
Ohori M, Wheeler TM, Kattan MW, Goto Y, Scardino PT (1995) Prognostic significance of positive surgical margins inradical prostatectomy specimens. J Urol 154:1818–1824.
Rosen MA, Goldstone L, Lapin S, Wheeler T, Scardino PT (1992) Frequency and location of extracapsular extension and positive surgical margins in radical prostatectomy specimens. J Urol 148:331–337.
Cheng L, Darson MF, Bergstrahl EJ, Slezak J, Meyers RP, Bostwick DG (1999) Correlation of margin status and extraprostatic extension with progression of prostate cancer. Cancer 86:1775–1782.
Epstein JI, Pizov G, Walsh PC (1993) Correlation of pathologic findings with progression after radical retropubic prostatectomy. Cancer 71:3583–3593.
Barocas DA, Han M, Epstein JI, Chan DY, Trock BJ, Walsh PC, Partin AW (2001) Does capsular incision at radical retropubic prostatectomy affect disease-free survival in otherwise organ-confined prostate cancer? Urology 58:746–751.
Rights and permissions
Copyright information
© 2008 Springer
About this chapter
Cite this chapter
(2008). A positive surgical margin associated with an extraprostatic extension of prostate carcinoma is a significant risk for disease progression. What, then, is the risk of a positive margin created by an inadvertent surgical incision into cancerous prostate parenchyma?. In: Questions in Daily Urologic Practice. Springer, Tokyo. https://doi.org/10.1007/978-4-431-72819-1_8
Download citation
DOI: https://doi.org/10.1007/978-4-431-72819-1_8
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-72818-4
Online ISBN: 978-4-431-72819-1
eBook Packages: MedicineMedicine (R0)