What is the difference between pheochromocytoma and paraganglioma? What are the familial syndromes that have pheochromocytoma as a component? What are the pathologic features of pheochromocytoma indicating malignancy?


The terms pheochromocytoma and paraganglioma are often used interchangeably because morphologically and functionally these entities are the same. Strictly speaking, however, paragangliomas that arise in the adrenal medulla are defined as pheochromocytomas, and those outside the adrenal gland are called paragangliomas. Most of pheochromocytomas and paragangliomas are functional, synthesizing and secreting catecholamines (epinephrine and norepinephrine).


Adrenal Medulla Multiple Endocrine Neoplasia Chief Cell Sustentacular Cell Adrenal Pheochromocytoma 
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