How does adrenal gland involvement by renal cell carcinoma affect the prognosis, if any? Should a tumor directly infiltrating the ipsilateral adrenal gland be kept as a pT3a tumor?
There have been several reliable reports that recommended cases of adrenal involvement by renal cell carcinoma (RCC) by direct invasion be removed from the pT3a category and moved to pT4 because of their grave prognosis, which is comparable to that of pT4 carcinoma.
KeywordsRenal Cell Carcinoma Adrenal Gland Adrenal Metastasis Direct Invasion AJCC Cancer Staging Manual
Unable to display preview. Download preview PDF.
- 7.Kobayashi T, Nakamura E, Yamamoto S, Kamoto T, Okuno H, Terai A, Kakehi Y, Terachi T, Fujikawa K, Fukuzawa S, Takeuchi H, Ogawa O (2003) Low incidence of ipsilateral adrenal involvement and recurrences in patients with renal cell carcinoma undergoing radical nephrectomy: a retrospective analysis of 393 patients. Urology 62:40–45.PubMedCrossRefGoogle Scholar