Are there immunohistochemical markers for the differential diagnosis of renal cell neoplasms, especially when tumor cells have an eosinophilic/granular cytoplasm?


Standard microscopic examination is sufficient for classifying most renal tumors, but there are occasions on which ancillary studies are helpful in reaching the final diagnosis. They are, in order of practical usefulness: immunohistochemistry, chromosomal analysis by fluorescence in situ hybridization (FISH), and molecular analysis. The last method should be considered for renal cell carcinomas arising in children or young adults.


Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Papillary Renal Cell Carcinoma Chromophobe Renal Cell Carcinoma Renal Oncocytoma 
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