Does a prostatic capsule exist? Pathologists and urologists use the word “capsule” when evaluating the extent of prostatic cancer in prostatectomy specimens
In a very strict sense, the prostate lacks an intact capsule. For practical reasons, however, the prostate has a capsule along its dorsolateral aspect extending from the base down close to the apical margin. The ventral (anterior) middle third does not have a capsule but, instead, is invested by a thick smooth muscle layer that extends dorsally (posteriorly) in the midline and invests the urethra as a preprostatic sphincter. We now prefer the term “extraprostatic extension” (EPE) when prostate cancer extends outside the prostate. This is to avoid the argument of the presence or absence of a prostatic capsule.
KeywordsRadical Prostatectomy Seminal Vesicle Smooth Muscle Layer Prostatectomy Specimen Apical Margin
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