Early Sensitization and Development of Allergic Airway Disease—Risk Factors and Predictors: Is the Adult Responder Phenotype Determined during Early Childhood?

  • Susanne Halken
  • Arne Høst
Part of the Allergy Frontiers book series (ALLERGY, volume 1)

Allergic airway diseases, i.e., allergic asthma and allergic rhinoconjunctivitis represent a heavy burden in childhood. In a recent prospective population-based study [1], the prevalence of current asthma and rhinitis was 14.4% and 15.1%, respectively, in 10-year-old unselected children, with a high degree of comorbidity as the prevalence of rhinitis was 42.5% in children with current asthma.

The allergens associated with allergic airway disease depend on the age, climatic, seasonal, and social factors, and housing conditions. In tempered and humid regions, allergy to house dust mites most often is associated with asthma followed by allergy to furred pets, whereas allergy to the fungus Alternaria spp. is important in arid climates in the USA and allergy to cockroach is important especially in urban communities in inner cities [2].


Allergic Disease Allergy Clin Immunol Atopic Disease Birth Cohort Study Bronchial Hyperresponsiveness 
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Copyright information

© Springer 2009

Authors and Affiliations

  • Susanne Halken
    • 1
  • Arne Høst
    • 1
  1. 1.Department of PediatricsOdense University HospitalOdense CDenmark

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